Background The scarcity of early biomarkers for acute renal failure has hindered our ability
to launch preventive and therapeutic measures for this disorder in a timely manner. We …

ABSTRACT. Acute renal failure (ARF) secondary to ischemic injury remains a common and
potentially devastating problem. A transcriptome-wide interrogation strategy was used to …

BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) appears to be a promising
biomarker for the early diagnosis of acute kidney injury (AKI); however, a wide range in …

Neutrophil gelatinase–associated lipocalin (Ngal), also known as siderocalin, forms a
complex with iron-binding siderophores (Ngal: siderophore: Fe). This complex converts renal …

Acute renal failure (ARF), classically defined as an abrupt decrease in kidney function that
leads to accumulation of nitrogenous wastes such as blood urea nitrogen and creatinine, is a …

Neutrophil gelatinase–associated lipocalin (NGAL) is expressed and secreted by immune
cells, hepatocytes, and renal tubular cells in various pathologic states. NGAL exerts …

Background and objectives: The authors have previously shown that urine neutrophil
gelatinase-associated lipocalin (NGAL), measured by a research ELISA, is an early predictive …

Background: A single serum creatinine measurement cannot distinguish acute kidney injury
from chronic kidney disease or prerenal azotemia. Objective: To test the sensitivity and …

Acute kidney injury (AKI) is a frequent complication of cardiopulmonary bypass (CPB). The
lack of early biomarkers for AKI has impaired our ability to intervene in a timely manner. …

Objectives : The aim of this study was to test the hypothesis that, without diagnostic changes
in serum creatinine, increased neutrophil gelatinase-associated lipocalin (NGAL) levels …