User profiles for Phoebe Sharp

Phoebe Sharp

- Verified email at gwu.edu - Cited by 78

Phoebe Sharp

- Verified email at gwmail.gwu.edu - Cited by 10

[HTML][HTML] The host cellular immune response to cytomegalovirus targets the endothelium and is associated with increased arterial stiffness in ANCA-associated …

D Chanouzas, M Sagmeister, L Dyall, P Sharp… - Arthritis research & …, 2018 - Springer
Background Cardiovascular disease is a leading cause of death in ANCA-associated vasculitis
(AAV). An expansion of CD4 + CD28 null T cells is seen mainly in cytomegalovirus (CMV)…

FcγRIIb on myeloid cells and intrinsic renal cells rather than B cells protects from nephrotoxic nephritis

PEH Sharp, J Martin-Ramirez, SM Mangsbo… - The Journal of …, 2013 - journals.aai.org
FcγRIIb is the sole inhibitory FcR for IgG in humans and mice, where it is involved in the
negative regulation of Ab production and cellular activation. FcγRIIb-deficient mice show …

Ultrasonic bone assessment using the backscatter amplitude decay constant

BK Hoffmeister, AJ Gray, PC Sharp… - Ultrasound in Medicine …, 2020 - Elsevier
Ultrasonic backscatter techniques are being developed to detect changes in bone caused by
osteoporosis. The present study introduces a new technique that measures the exponential …

Effect of treatment on damage and hospitalization in elderly patients with microscopic polyangiitis and granulomatosis with polyangiitis

…, Z Hrušková, A Tanna, P Sharp… - The Journal of …, 2020 - jrheum.org
Objective. Age is a risk factor for organ damage, adverse events, and mortality in microscopic
polyangiitis (MPA) and granulomatosis with polyangiitis (GPA). However, the relationship …

Increased incidence of anti-GBM disease in Fcgamma receptor 2b deficient mice, but not mice with conditional deletion of Fcgr2b on either B cells or myeloid cells …

PEH Sharp, J Martin-Ramirez, P Boross… - Molecular …, 2012 - Elsevier
Fcgamma receptor 2b (Fcgr2b) is the only inhibitory Fcgamma receptor in both humans and
mice, and is implicated in both antibody production and effector responses to antibody …

[HTML][HTML] Mice with defective Fas ligand are protected from crescentic glomerulonephritis

RM Tarzi, PEH Sharp, JP McDaid, L Fossati-Jimack… - Kidney international, 2012 - Elsevier
Fas ligand is a well-known inducer of apoptosis in cells expressing its receptor Fas; it also
prevents autoimmunity by inducing apoptosis of activated T cells. However, Fas ligand also …

The changing pattern of synthetic cannabinoid use within England, April 2014 to March 2018

P Sharp, S Hudson, L Hikin… - … , Science and the …, 2019 - journals.sagepub.com
Introduction Synthetic cannabinoids (SC), designed to mimic delta-9-tetrahydrocannabinol,
the natural component of cannabis, have seen a rapid increase in popularity since 2008. …

[PDF][PDF] Precision measurements of A= 3 nuclei in Hall B

…, B Raue, R Santos, E Segarra, P Sharp… - arXiv preprint arXiv …, 2020 - researchgate.net
We propose a high-statistics measurement of few body nuclear structure and short range
correlations in quasi-elastic scattering at 6.6 GeV from 2H, 3He and 3H targets in Hall B with …

Quantitation of Synthetic Cannabinoid Receptor Agonists in Postmortem Blood Using a Single Point Calibration

P Sharp, S Hudson, SR Morley - Academic Forensic …, 2021 - journals.sagepub.com
Synthetic cannabinoid receptor agonists (SCRA) share minimal structural similarities to
tetrahydrocannabinol or themselves. Due to their heterogeneous structures and the rapid …

[BOOK][B] Mechanisms of injury in experimental glomerulonephritis

P Sharp - 2014 - core.ac.uk
Proliferative glomerulonephritis (GN), seen in patients with Goodpasture’s disease or systemic
lupus erythematosus (SLE), is characterised by glomerular infiltration of macrophages …