Analytical characteristics of high-sensitivity cardiac troponin assays
FS Apple, PO Collinson… - Clinical …, 2012 - academic.oup.com
BACKGROUND Cardiac troponins I (cTnI) and T (cTnT) have received international endorsement
as the standard biomarkers for detection of myocardial injury, for risk stratification in …
as the standard biomarkers for detection of myocardial injury, for risk stratification in …
[HTML][HTML] High-sensitivity cardiac troponin I at presentation in patients with suspected acute coronary syndrome: a cohort study
…, A Ferry, AG Stirzaker, A Reid, AJ Gray, PO Collinson… - The Lancet, 2015 - thelancet.com
Background Suspected acute coronary syndrome is the commonest reason for emergency
admission to hospital and is a large burden on health-care resources. Strategies to identify …
admission to hospital and is a large burden on health-care resources. Strategies to identify …
High sensitivity cardiac troponin and the under-diagnosis of myocardial infarction in women: prospective cohort study
…, M Stoddart, F Strachan, S Walker, PO Collinson… - bmj, 2015 - bmj.com
Objective To evaluate the diagnosis of myocardial infarction using a high sensitivity troponin
I assay and sex specific diagnostic thresholds in men and women with suspected acute …
I assay and sex specific diagnostic thresholds in men and women with suspected acute …
Cardiac troponins: from myocardial infarction to chronic disease
Elucidation of the physiologically distinct subunits of troponin in 1973 greatly facilitated our
understanding of cardiac contraction. Although troponins are expressed in both skeletal and …
understanding of cardiac contraction. Although troponins are expressed in both skeletal and …
Ischemia modified albumin is a sensitive marker of myocardial ischemia after percutaneous coronary intervention
MK Sinha, DC Gaze, JR Tippins, PO Collinson… - Circulation, 2003 - Am Heart Assoc
Background— Ischemia modified albumin (IMA; Ischemia Technologies, Inc) blood levels
rise in patients who develop ischemia during percutaneous coronary intervention (PCI). It is …
rise in patients who develop ischemia during percutaneous coronary intervention (PCI). It is …
Measurement of cardiac troponins
PO Collinson, FG Boa, DC Gaze - Annals of clinical …, 2001 - journals.sagepub.com
The cardiac troponins form part of the regulatory mechanism for muscle contraction. Specific
cardiac isoforms of cardiac troponin T and cardiac troponin I exist and commercially …
cardiac isoforms of cardiac troponin T and cardiac troponin I exist and commercially …
[HTML][HTML] High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial
…, A Cruickshank, A Reid, A Gray, PO Collinson… - The Lancet, 2018 - thelancet.com
Background High-sensitivity cardiac troponin assays permit use of lower thresholds for the
diagnosis of myocardial infarction, but whether this improves clinical outcomes is unknown. …
diagnosis of myocardial infarction, but whether this improves clinical outcomes is unknown. …
[HTML][HTML] Exercise-induced cardiac troponin T release: a meta-analysis
…, DC Gaze, PO Collinson - … & Science in …, 2007 - westminsterresearch.westminster.ac …
PURPOSE: Cardiac troponin T (cTnT) is a highly specific marker of myocardial damage and
used clinically in the diagnosis of acute myocardial infarction (AMI). Release of cTnT has …
used clinically in the diagnosis of acute myocardial infarction (AMI). Release of cTnT has …
Influence of population selection on the 99th percentile reference value for cardiac troponin assays
PO Collinson, YM Heung, D Gaze, F Boa… - Clinical …, 2012 - academic.oup.com
OBJECTIVE We sought to determine the effect of patient selection on the 99th reference
percentile of 2 sensitive and 1 high-sensitivity (hs) cardiac troponin assays in a well-defined …
percentile of 2 sensitive and 1 high-sensitivity (hs) cardiac troponin assays in a well-defined …
Meta-analysis of ischemia-modified albumin to rule out acute coronary syndromes in the emergency department
…, S Anwaruddin, RH Christenson, PO Collinson… - American heart …, 2006 - Elsevier
BACKGROUND: Because of possible adverse outcomes, many of the >6 million annual
emergency department (ED) patients with suspected acute coronary syndromes (ACS) undergo …
emergency department (ED) patients with suspected acute coronary syndromes (ACS) undergo …