Background Autoinflammatory diseases manifest inflammation without evidence of infection,
high-titer autoantibodies, or autoreactive T cells. We report a disorder caused by mutations …

Objective To describe clinical outcomes of juvenile idiopathic arthritis (JIA) in a prospective
inception cohort of children managed with contemporary treatments. Methods Children newly …

BACKGROUND Undifferentiated systemic autoinflammatory diseases (USAIDs) present
diagnostic and therapeutic challenges. Chronic interferon (IFN) signaling and cytokine …

Objective To uniquely classify children with microscopic polyangiitis (MPA), to describe their
demographic characteristics, presenting clinical features, and initial treatments in …

Objective To determine early outcomes and early improvements in a prospective inception
cohort of children with juvenile idiopathic arthritis (JIA) treated with current standard therapies…

Objective To describe probabilities and characteristics of disease flares in children with juvenile
idiopathic arthritis (JIA) and to identify clinical features associated with an increased risk …

Objective To determine early predictors of 6‐month outcomes in a prospective cohort of
patients with juvenile idiopathic arthritis (JIA). Methods Patients selected were those enrolled in …

Objective Childhood arthritis encompasses a heterogeneous family of diseases. Significant
variation in clinical presentation remains despite consensus‐driven diagnostic classifications…

Objective To describe changes in health‐related quality of life ( HRQ oL) over time in children
with juvenile idiopathic arthritis ( JIA ), relative to other outcomes, and to identify predictors …

Objective Individuals with deficiency of adenosine deaminase 2 ( DADA 2), a recently recognized
autosomal recessive disease, present with various systemic vascular and inflammatory …