A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated
variants with diverse genomic and biological data sets to provide insight into …

Background Various observations have suggested that the course of COVID-19 might be
less favourable in patients with inflammatory rheumatic and musculoskeletal diseases …

Background Given the phenotypic similarities between rheumatoid arthritis (RA)–associated
interstitial lung disease (ILD) (hereafter, RA-ILD) and idiopathic pulmonary fibrosis, we …

Objective. To measure the prevalence of different types of pulmonary hypertension (PH) and
to identify patients with systemic sclerosis (SSc) at highest risk in a multicenter European …

Rheumatoid arthritis (RA) is a highly heritable complex disease with unknown etiology. Multi-ancestry
genetic research of RA promises to improve power to detect genetic signals, fine-…

Systemic sclerosis (SSc) is an orphan, complex, inflammatory disease affecting the immune
system and connective tissue. SSc stands out as a severely incapacitating and life-…

Objectives To analyze the clinical and immunological characteristics at enrollment in a large
prospective cohort of patients with primary Sjögren's syndrome (pSS) and to investigate the …

A polymorphism on the MUC5B promoter (rs35705950) has been associated with idiopathic
pulmonary fibrosis (IPF) but not with systemic sclerosis (SSc) with interstitial lung disease (…

Introduction Gout is a common arthritis that occurs particularly in patients who frequently have
associated comorbidities that limit the use of conventional therapies. The main mechanism …

Objective. To investigate whether levels of anti-cyclic citrullinated peptide antibodies (anti-CCP2)
in patients with rheumatoid arthritis (RA) are associated with the co-occurrence of lung …