Delay to institution of therapy and induction of remission using single‐drug or combination–disease‐modifying antirheumatic drug therapy in early rheumatoid arthritis

T Möttönen, P Hannonen, M Korpela… - … : Official Journal of …, 2002 - Wiley Online Library
Objective To study the impacts of 1) the delay from the onset of symptoms to the institution of
disease‐modifying antirheumatic drug (DMARD) therapy, 2) two treatment strategies (…

Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: a randomised trial

T Möttönen, P Hannonen, M Leirisalo-Repo, M Nissilä… - The Lancet, 1999 - thelancet.com
Background The treatment of rheumatoid arthritis should aim at clinical remission. This
multicentre, randomised trial with 2-year follow-up sought evidence on the efficacy and tolerability …

Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force

…, JJ Gomez-Reino, W Graninger, P Hannonen… - Annals of the …, 2016 - ard.bmj.com
Background Reaching the therapeutic target of remission or low-disease activity has
improved outcomes in patients with rheumatoid arthritis (RA) significantly. The treat-to-target …

A randomized two‐year study of the effects of dynamic strength training on muscle strength, disease activity, functional capacity, and bone mineral density in early …

…, T Sokka, A Kotaniemi, P Hannonen - Arthritis & …, 2001 - Wiley Online Library
Objective To evaluate the impact of a 2‐year program of strength training on muscle strength,
bone mineral density (BMD), physical function, joint damage, and disease activity in …

Retardation of joint damage in patients with early rheumatoid arthritis by initial aggressive treatment with disease‐modifying antirheumatic drugs: five‐year experience …

M Korpela, L Laasonen, P Hannonen… - … : Official Journal of …, 2004 - Wiley Online Library
Objective To evaluate the long‐term frequency of disease remissions and the progression of
joint damage in patients with early rheumatoid arthritis (RA) who were initially randomized …

Early suppression of disease activity is essential for maintenance of work capacity in patients with recent‐onset rheumatoid arthritis: five‐year experience from the FIN …

…, H Kautiainen, T Möttönen, P Hannonen… - … : Official Journal of …, 2005 - Wiley Online Library
Objective To explore the impact of an early treatment response on maintenance of work
capacity in patients with early, active rheumatoid arthritis (RA). Methods In the Finnish …

Is DAS28 an appropriate tool to assess remission in rheumatoid arthritis?

H Mäkinen, H Kautiainen, P Hannonen… - Annals of the Rheumatic …, 2005 - ard.bmj.com
Objectives: To study which cut off point of DAS28 corresponds to fulfilment of the American
Rheumatism Association (ARA) preliminary remission criteria, and clinical remission criteria …

Normative values for the Health Assessment Questionnaire disability index: benchmarking disability in the general population

…, A Häkkinen, H Hubert, P Hannonen - Arthritis & …, 2004 - Wiley Online Library
Objective The Health Assessment Questionnaire (HAQ) disability index (DI) has been
commonly used in rheumatology to quantify functional disability in patient groups, but current …

Impact of initial aggressive drug treatment with a combination of disease‐modifying antirheumatic drugs on the development of work disability in early rheumatoid …

…, H Kautiainen, T Möttönen, P Hannonen… - … : Official Journal of …, 2004 - Wiley Online Library
Objective To compare the efficacy of therapy with a combination of disease‐modifying
antirheumatic drugs (DMARDs) versus therapy with a single DMARD in the prevention of work …

Functional disability in rheumatoid arthritis patients compared with a community population in Finland

…, E Krishnan, A Häkkinen, P Hannonen - Arthritis & …, 2003 - Wiley Online Library
Objective To compare Health Assessment Questionnaire (HAQ) scores of patients with
rheumatoid arthritis (RA) with HAQ scores from a sex‐ and age‐adjusted population. Methods …