Osteoarthritis: new insights. Part 1: the disease and its risk factors

DT Felson, RC Lawrence, PA Dieppe… - Annals of internal …, 2000 - acpjournals.org
Osteoarthritis is the most common form of arthritis, affecting millions of people in the United
States. It is a complex disease whose etiology bridges biomechanics and biochemistry. …

Pathogenesis and management of pain in osteoarthritis

PA Dieppe, LS Lohmander - The Lancet, 2005 - thelancet.com
The term osteoarthritis describes a common, age-related, heterogeneous group of disorders
characterised pathologically by focal areas of loss of articular cartilage in synovial joints, …

Osteoarthritis: new insights. Part 2: treatment approaches

…, MC Hochberg, T McAlindon, PA Dieppe… - Annals of internal …, 2000 - acpjournals.org
Osteoarthritis is the most common form of arthritis, affecting millions of people in the United
States. It is a complex disease whose etiology bridges biomechanics and biochemistry. …

Guidelines for the medical management of osteoarthritis. Part II. Osteoarthritis of the knee. American College of Rheumatology.

…, KD Brandt, BM Clark, PA Dieppe… - Arthritis and …, 1995 - europepmc.org
A comment on this article appears in" Fluoroscopically directed steroid instillation in the
treatment of hip osteoarthritis: safety and efficacy in 510 cases." Arthritis Rheum. 2001 Oct; 44 (10…

Risk of cardiovascular events and rofecoxib: cumulative meta-analysis

P Jüni, L Nartey, S Reichenbach, R Sterchi, PA Dieppe… - The lancet, 2004 - thelancet.com
Background The cyclo-oxygenase 2 inhibitor rofecoxib was recently withdrawn because of
cardiovascular adverse effects. An increased risk of myocardial infarction had been observed …

Risk factors for the incidence and progression of radiographic knee osteoarthritis

…, B Stuart, D Coggon, PA Dieppe - … : Official Journal of …, 2000 - Wiley Online Library
Objective Preventive strategies against knee osteoarthritis (OA) require a knowledge of risk
factors that influence the initiation of the disorder and its subsequent progression. This …

The placebo effect and its determinants in osteoarthritis: meta-analysis of randomised controlled trials

W Zhang, J Robertson, AC Jones, PA Dieppe… - Annals of the …, 2008 - ard.bmj.com
Objective: To examine the placebo effect and its potential determinants in the treatment of
osteoarthritis (OA) via a systematic literature search of Medline, EMBASE, Scientific Citation …

Are selective COX 2 inhibitors superior to traditional non steroidal anti-inflammatory drugs?: Adequate analysis of the CLASS trial indicates that this may not be the …

P Jüni, AWS Rutjes, PA Dieppe - Bmj, 2002 - bmj.com
(Vioxx), are hypothesised to have a lower risk of gastrointestinal complications than
traditional nonsteroidal anti-inflammatory drugs. 1 In September 2000 the celecoxib long term …

Meta-analysis: chondroitin for osteoarthritis of the knee or hip

…, S Trelle, E Bürgi, U Bürgi, PA Dieppe… - Annals of internal …, 2007 - acpjournals.org
Background: Previous meta-analyses described moderate to large benefits of chondroitin in
patients with osteoarthritis. However, recent large-scale trials did not find evidence of an …

Predictors of outcomes of total knee replacement surgery

…, M Kassim Javaid, AJ Carr, RE Field, PA Dieppe - …, 2012 - academic.oup.com
Objective. To identify pre-operative predictors of patient-reported outcomes of primary total
knee replacement (TKR) surgery. Methods. The Elective Orthopaedic Centre database is a …