[HTML][HTML] Gut microbiota-host interactions and juvenile idiopathic arthritis

…, L Berntson, T Pokka, TJ Karttunen, P Vähäsalo… - Pediatric …, 2016 - Springer
… A similar, albeit not statistically significant (21 % versus 11 %, P = 0.150) increase in the
Bacteroides genus was also observed in the feces of a cohort of 25 children with enthesitis-…

Genetic, autoimmune, and clinical characteristics of childhood-and adult-onset type 1 diabetes.

…, K Savola, T Ebeling, P Kulmala, P Vähäsalo… - Diabetes …, 2000 - Am Diabetes Assoc
OBJECTIVE: To assess whether there are any differences in genetic, autoimmune, or
clinical features between type 1 diabetes presenting in childhood and that diagnosed later. …

Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group.

…, K Savola, JS Petersen, P Vähäsalo… - The Journal of …, 1998 - Am Soc Clin Investig
… A two-tailed P value of 0.05 was considered to indicate statistical significance. All the
statistical analyses were performed using the SPSS statistical software package (SPSS Inc., …

Aggressive combination drug therapy in very early polyarticular juvenile idiopathic arthritis (ACUTE–JIA): a multicentre randomised open-label clinical trial

P Tynjälä, P Vähäsalo, M Tarkiainen… - Annals of the …, 2011 - ard.bmj.com
… in both panels A and C were significant; p<0.0001 and p=0.002, respectively. Error bars …
p=0.003). Drug survival rates were higher for TNF than for methotrexate (p=0.001) or COMBO (p

Infliximab or etanercept in the treatment of children with refractory juvenile idiopathic arthritis: an open label study

P Lahdenne, P Vähäsalo, V Honkanen - Annals of the rheumatic …, 2003 - ard.bmj.com
p Values between groups were calculated by the permutation test with Monte-Carlo
estimates. Differences in drug withdrawal between the groups were estimated by the Wilcoxon-…

IA-2 antibodies–a sensitive marker of IDDM with clinical onset in childhood and adolescence

…, E Bonifacio, E Sabbah, P Kulmala, P Vähäsalo… - Diabetologia, 1998 - Springer
… (83.3 vs 85.7%, p = 0.98), and there was no significant difference in the IA-2A levels between
those carrying the DR2 allele and the others (3.2 vs 44.2 RU; p = 0.23). The frequencies of …

Diabetes-associated autoantibodies in relation to clinical characteristics and natural course in children with newly diagnosed type 1 diabetes

…, P Kulmala, R Veijola, P Vähäsalo… - The Journal of …, 1999 - academic.oup.com
… (P = 0.01). Autoantibody-negative subjects needed less exogenous insulin at 6 and 18 (P =
0.01) and at 24 months (P < … in clinical remission at 18 months (P < 0.001). We conclude that …

Phenotypic variability and disparities in treatment and outcomes of childhood arthritis throughout the world: an observational cohort study

…, E Unsal, Y Uziel, P Vähäsalo… - The Lancet Child & …, 2019 - thelancet.com
Background To our knowledge, the characteristics and burden of childhood arthritis have
never been studied on a worldwide basis. We aimed to investigate, with a cross-sectional study…

Enterovirus infections are associated with the induction of β‐cell autoimmunity in a prospective birth cohort study

…, K Sadeharju, M Lönnrot, P Vähäsalo… - Journal of medical …, 2003 - Wiley Online Library
… (P = 0.004), and the average enterovirus antibody levels were also higher in the case children
(P … children had an infection in that time interval (P = 0.003). There was no difference in the …

Predictive characteristics of diabetes-associated autoantibodies among children with HLA-conferred disease susceptibility in the general population

…, S Simell, A Hekkala, J Lähde, T Simell, P Vähäsalo… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE As data on the predictive characteristics of diabetes-associated autoantibodies
for type 1 diabetes in the general population are scarce, we assessed the predictive …