Objective To examine the safety and efficacy of the interleukin‐1 (IL‐1) receptor antagonist
anakinra as first‐line therapy for systemic juvenile idiopathic arthritis (JIA). Methods Patients …

SIR, Macrophage activation syndrome (MAS) belongs to the haemophagocytic lymphohistiocytic
(HLH) disorders, and is one of the most feared complications of paediatric inflammatory …

Objective To formulate consensus treatment plans (CTPs) for induction therapy of newly
diagnosed proliferative lupus nephritis (LN) in juvenile systemic lupus erythematosus (SLE). …

Objective To determine the frequency of incident vertebral fractures (IVF) 12 months after
glucocorticoid (GC) initiation in children with rheumatic diseases and to identify children at …

Purpose Vertebral fractures due to osteoporosis are a potential complication of childhood
acute lymphoblastic leukemia (ALL). To date, the incidence of vertebral fractures during ALL …

Objectives: The purpose of this article was to determine the incidence and predictors of
vertebral fractures (VF) during the 4 years after diagnosis in pediatric acute lymphoblastic …

… PM Miettunen, MD, Division of Rheumatology, Department of Pediatrics, University of
Calgary; O. Ortiz-… Miettunen was supported by a fellowship from The Arthritis Society, Canada. …

Objective. To determine the incidence and longitudinal trends of Wegener’s granulomatosis
(WG) in the pediatric population of Southern Alberta over the last 15 years. Results. Fifteen …

Objective To describe changes in health‐related quality of life ( HRQ oL) over time in children
with juvenile idiopathic arthritis ( JIA ), relative to other outcomes, and to identify predictors …

Background Confirmation of early long-bone epiphyseal osteonecrosis in pediatric patients
with leukemia allows for medical and surgical intervention before articular surface collapse. …