The nuclear protein high mobility group box 1 (HMGB1) has been suggested to be involved
in the pathogenesis of several vascular diseases such as systemic vasculitis and …

Proteinase 3 (PR3) is one of four serine protease homologues in the azurophilic granules of
neutrophils and granules of monocytes. It is of importance that anti-neutrophil cytoplasmic …

The importance of p38 MAPK inhibitors as new drug for rheumatoid arthritis is reflected by
the large number of compounds that has been developed over the last years. In this review …

To evaluate the predictive power of changes in levels of antibodies to double‐stranded DNA
(anti‐dsDNA) as a predictor of disease exacerbations in systemic lupus erythematosus (SLE…

Objective Prediction of relapses in Wegener's granulomatosis (WG) by measuring levels of
antineutrophil cytoplasmic antibodies (ANCA) directed against proteinase 3 (PR3) or …

Objectives: Procalcitonin (PCT) is a 13 kD protein of which plasma concentrations are
strongly increased in inflammatory states. PCT concentrations are claimed to have a more …

During the acute phase response, synthesis of C-reactive protein and serum amyloid A is
increased. To investigate whether the enhanced synthesis of these proteins are due to …

Objective To investigate the relationship between different outcome and process measures
in early rheumatoid arthritis (RA). Methods A 3-year prospective study of 149 patients with …

The bacterial flora in the human colon, although extremely diverse, has a relatively stable
composition and non-infectious anaerobic bacteria are dominant. The flora forms a pool of …

To define the toxicity profile of recombinant human interleukin-6 (rhIL- 6) and to study its effect
on hematopoiesis, biochemical parameters and other cytokines, rhIL-6 was administered …