MRP‐8 and MRP‐14, two abundant Ca2+‐binding proteins of neutrophils and monocytes

PA Hessian, J Edgeworth… - Journal of leukocyte …, 1993 - Wiley Online Library
Two calrium‐binding proteins, named migration inhibitory factor‐related proteins‐8 (MRP‐8)
and MRP‐14, are primarily expressed by circulating human neutrophils and monocytes. …

Cytokine profile of the rheumatoid nodule suggests that it is a Th1 granuloma

PA Hessian, J Highton, A Kean, CK Sun… - Arthritis & …, 2003 - Wiley Online Library
Objective To define the cytokine profile within rheumatoid subcutaneous nodules, and to
determine whether the destructive inflammatory process in this lesion displays features of a …

Role of hepatic stellate cell/hepatocyte interaction and activation of hepatic stellate cells in the early phase of liver regeneration in the rat

A Mabuchi, I Mullaney, PW Sheard, PA Hessian… - Journal of …, 2004 - Elsevier
BACKGROUND/AIMS: Hepatic stellate cells (HSCs) are known to play a role in hepatic
regeneration. We investigated hepatocyte/HSC interaction and HSC activation at various times …

[HTML][HTML] Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action

…, C Frampton, J Highton, PA Hessian - Arthritis research & …, 2012 - Springer
Introduction Methotrexate (MTX) exerts at least part of its anti-inflammatory effects through
adenosine receptors (ADOR). The aims of this study were to determine the expression of all …

[HTML][HTML] The G82S polymorphism promotes glycosylation of the receptor for advanced glycation end products (RAGE) at asparagine 81: comparison of wild-type rage …

SJ Park, T Kleffmann, PA Hessian - Journal of Biological Chemistry, 2011 - ASBMB
Interaction between the receptor for advanced glycation end products (RAGE) and its
ligands amplifies the proinflammatory response. N-Linked glycosylation of RAGE plays an …

[HTML][HTML] Dendritic cells provide a potential link between smoking and inflammation in rheumatoid arthritis

…, J Highton, LK Stamp, PA Hessian - Arthritis research & …, 2012 - Springer
Introduction Smoking increases the risk of developing rheumatoid arthritis (RA) and affects
the severity of established RA. Smoking can impact on Th17 lymphocyte differentiation and …

Pathogenic mechanisms in the rheumatoid nodule: comparison of proinflammatory cytokine production and cell adhesion molecule expression in rheumatoid nodules …

…, A Parker, M Coleman, PA Hessian… - … : Official Journal of …, 1998 - Wiley Online Library
… Palmer DG; Hogg N, Allen CA, Highton J: Hessian PA. A mononuclear phagocytc subset …
Palmer DG, Smith M, Hessian PA. Phenotypic markers of lymphocyte and inononuclcar …

[HTML][HTML] Greenshell™ mussels: a review of veterinary trials and future research directions

…, N King, S Johns, E Forbes-Blom, PA Hessian… - Veterinary …, 2018 - mdpi.com
The therapeutic benefits of Greenshell™ mussel (GSM; Perna canaliculus) preparations have
been studied using in vitro test systems, animal models, and human clinical trials focusing …

IL-23R rs11209026 polymorphism modulates IL-17A expression in patients with rheumatoid arthritis

…, LK Stamp, T Merriman, J Highton, PA Hessian - Genes & …, 2012 - nature.com
The interleukin (IL)-17/IL-23 axis is an important pro-inflammatory pathway in rheumatoid
arthritis (RA). IL-23 maintains CD4+ T-helper 17 (Th 17) cells, whereas IL-12 negates IL-17A …

The heterodimeric complex of MRP‐8 (S100A8) and MRP‐14 (S100A9) Antibody recognition, epitope definition and the implications for structure

PA Hessian, L Fisher - European journal of biochemistry, 2001 - Wiley Online Library
… To date, S100B, S100A6, and S100P as well as S100A7 [35], MRP-8 and MRP-14 [27,36]
(this report and PA Hessian, unpublished data) have all been shown to form noncovalent …