… 1-2 was first purified from skeletal muscle by Foulkes & Cohen (1 1 5), although improved
isolation procedures have been published subsequently (1 16--1 1 8). It has also been …

Protein kinases regulate nearly all aspects of cell life, and alterations in their expression, or
mutations in their genes, cause cancer and other diseases. Here, we review the remarkable …

Protein phosphorylation regulates most aspects of cell life, whereas abnormal phosphorylation
is a cause or consequence of disease. A growing interest in developing orally active …

… We say P forces Fa e Fe if for some 13' <1, P forces Fag e Fee … We say P forces 7 FaE F,6if
for all 1' <1 and P' D P, P' doesnot … P, there is P' D P such that either )I" forces a or P'forces 7 a. …

… ,4,5-triphosphate (PtdIns(3,4,5)P 3 ) or PtdIns(3,4)P 2 were effective in potently activating the
kinase, which has been named PtdIns(3,4,5)P 3 -dependent protein kinase-1 (PDK1). None …

The specificities of 28 commercially available compounds reported to be relatively selective
inhibitors of particular serine/threonine-specific protein kinases have been examined …

Insulin activated endogenous protein kinase B alpha (also known as RAC/Akt kinase) activity
12‐fold in L6 myotubes, while after transfection into 293 cells PKBalpha was activated 20‐ …

… the presence of rapamycin and PD 98059) increased the "Plabelling of GSK3-o and GSK3-B
by 60 100% (Fig. 4c) and increased the "P-labelling of the same tryptic peptides labelled in …

… analysis tor the behavioral sciences I Jacob Cohen, Patricia Cohen. 2nd Ed. 1983. … This
book had its origin over 30 years ago, when it became apparent to Jack Cohen that there were …

… Although Paul Cohen’s reputation will forever be defined by his Fields Medal winning …
Thus, if we define p(n) as l or 0 according as An is true or false we can ask if p(n) is general …