[HTML][HTML] Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment

E Walker, M Ohishi, RE Davey, W Zhang, PA Cassar… - Cell stem cell, 2007 - cell.com
Stem cell fate is governed by the integration of intrinsic and extrinsic positive and negative
signals upon inherent transcriptional networks. To identify novel embryonic stem cell (ESC) …

Clinical use and interpretation of serum protein electrophoresis and adjunct assays

AYS Lee, PM Cassar, AM Johnston… - British Journal of …, 2017 - magonlinelibrary.com
Introduction: what is the test? Separation of different analytes in body fluids is useful to
distinguish individual components that may be contributing to pathology. Electrophoresis is a …

Association between insulin-like growth factor status and physical activity levels in rheumatoid arthritis.

A Lemmey, P Maddison, A Breslin, P Cassar… - The Journal of …, 2001 - jrheum.org
… a low level of exercise (p < 0.001) and a high percentage body fat (p < 0.001) in comparison
… with rheumatic diseases than in the healthy controls (p < 0.001). In this respect RA patients …

[HTML][HTML] Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge

B Raman, MP Cassar, EM Tunnicliffe, N Filippini… - …, 2021 - thelancet.com
… in COVID-19 (p-values for comparisons are from Student's t-tests for all variables; Spearman's
correlation coefficient and p-values are reported for correlations, # signifies p-values were …

Integrative genomics positions MKRN 1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network

PA Cassar, RL Carpenedo, P Samavarchi‐Tehrani… - EMBO …, 2015 - embopress.org
… components of ribonucleoprotein complexes (P = 1.1E‐34), and many are known to function
in posttranscriptional gene regulation (P = 4.2E‐12) and/or translational control (P = 2.6E‐06…

[HTML][HTML] Research ethics and stem cells: Is it time to re‐think current approaches to oversight?

…, A Zarzeczny, J Baltz, S Benjaminy, PA Cassar… - EMBO …, 2015 - embopress.org
Few areas of scientific inquiry have received the amount of attention from politicians, the media
and the ethics community that research involving human stem cells has received. A large …

[HTML][HTML] Symptom persistence despite improvement in cardiopulmonary health–insights from longitudinal CMR, CPET and lung function testing post-COVID-19

MP Cassar, EM Tunnicliffe, N Petousi… - …, 2021 - thelancet.com
Background The longitudinal trajectories of cardiopulmonary abnormalities and symptoms
following infection with coronavirus disease (COVID-19) are unclear. We sought to describe …

[HTML][HTML] Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study

B Raman, C McCracken, MP Cassar… - The Lancet …, 2023 - thelancet.com
Introduction The multiorgan impact of moderate to severe coronavirus infections in the post-acute
phase is still poorly understood. We aimed to evaluate the excess burden of multiorgan …

[HTML][HTML] Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised …

LEM Finnigan, MP Cassar, MJ Koziel, J Pradines… - …, 2023 - thelancet.com
… Dynamic 31 P-MRS permits assessment of the bioenergetic response of 31 P metabolites
to exercise. Upon exercise cessation, the phosphocreatine recovery rate serves as a marker of …

The use of umbilical stem cells

P Cassar, R Blundell - 2016 - um.edu.mt
The use of umbilical stem cells in tissue engineering is gaining in popularity. Some of the
various uses of these umbilical stem cells are highlighted in this review, focusing mainly on …