The gamete fusion process is defective in eggs of Cd9-deficient mice

…, T Ohnuki, Y Uematsu, J Sakagami, N Tada… - Nature …, 2000 - nature.com
The cell-surface molecule Cd9, a member of the transmembrane-4 superfamily 1, interacts
with the integrin family 2 and other membrane proteins 3, 4, 5, and is postulated to participate …

Liver autophagy contributes to the maintenance of blood glucose and amino acid levels

…, J Iwata, I Tanida, N Furuya, DM Zheng, N Tada… - Autophagy, 2011 - Taylor & Francis
Both anabolism and catabolism of the amino acids released by starvation-induced autophagy
are essential for cell survival, but their actual metabolic contributions in adult animals are …

Osteopontin plays an important role in the development of medial thickening and neointimal formation

…, M Yoshida, M Kusuhara, M Moroi, N Tada… - Circulation …, 2002 - Am Heart Assoc
Osteopontin (OPN) is a soluble secreted phosphoprotein that binds with high affinity to several
integrins and it has been found at the site of atherosclerotic lesions. However, the role of …

[HTML][HTML] A novel type of E3 ligase for the Ufm1 conjugation system

K Tatsumi, Y Sou, N Tada, E Nakamura… - Journal of biological …, 2010 - ASBMB
The ubiquitin fold modifier 1 (Ufm1) is the most recently discovered ubiquitin-like modifier
whose conjugation (ufmylation) system is conserved in multicellular organisms. Ufm1 is known …

Molecular Iodine Catalyzed Cross-Dehydrogenative Coupling Reaction between Two sp3 C–H Bonds Using Hydrogen Peroxide

T Nobuta, N Tada, A Fujiya, A Kariya, T Miura… - Organic letters, 2013 - ACS Publications
A useful method for molecular iodine catalyzed oxidative C–C bond formation between
tertiary amines and a carbon nucleophile using hydrogen peroxide as the terminal oxidant is …

Metal‐Free Direct C H Perfluoroalkylation of Arenes and Heteroarenes Using a Photoredox Organocatalyst

L Cui, Y Matusaki, N Tada, T Miura… - … Synthesis & Catalysis, 2013 - Wiley Online Library
We report the visible‐light‐induced trifluoromethylation of arenes and heteroarenes using
sodium trifluoromethanesulfinate catalyzed by anthraquinone‐2‐carboxylic acid. This reaction …

[HTML][HTML] Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer

…, T Mikami, N Inohara, K Matsushima, N Tada… - Nature …, 2021 - nature.com
Interleukin (IL)-11 is a member of the IL-6 family of cytokines and is involved in multiple
cellular responses, including tumor development. However, the origin and functions of IL-11-…

Activated Iodosylbenzene monomer as an ozone equivalent: oxidative cleavage of carbon− carbon double bonds in the presence of water

K Miyamoto, N Tada, M Ochiai - Journal of the American Chemical …, 2007 - ACS Publications
Reported here for the first time are the developments of an efficient method for oxidative
cleavage of carbon−carbon double bonds yielding carbonyl compounds by using aryl-λ 3 -…

[HTML][HTML] Macrophage-and neutrophil-dominant arthritis in human IL-1α transgenic mice

…, Y Toyama, K Fujikawa, N Tada - The Journal of …, 2001 - Am Soc Clin Investig
To study the effects of IL-1α in arthritis, we generated human IL-1α (hIL-1α). Transgenic
mice expressed hIL-1α mRNA in various organs, had high serum levels of hIL-1α, and …

Osteopontin transgenic mice fed a high-cholesterol diet develop early fatty-streak lesions

K Isoda, Y Kamezawa, M Ayaori, M Kusuhara, N Tada… - Circulation, 2003 - Am Heart Assoc
Background— Osteopontin (OPN) is a noncollagenous adhesion protein found at the site of
atherosclerotic lesions. However, it has not yet been clarified whether or not OPN can …