Measles virus continues to be a major killer of children, claiming roughly one million lives a
year 1 . Measles virus infection causes profound immunosuppression, which makes measles …

Both CD46 and signaling lymphocytic activation molecule (SLAM) have been shown to act
as cellular receptors for measles virus (MV). The viruses on throat swabs from nine patients …

Morbilliviruses comprise measles virus, canine distemper virus, rinderpest virus, and several
other viruses that cause devastating human and animal diseases accompanied by severe …

Pathogens or pathogen-associated molecular patterns can signal to cells of the innate immune
system and trigger effective adaptive immunity. However, relatively little is known about …

TNF-α antagonists are widely used in the treatment of inflammatory and autoimmune
diseases, but their use is associated with reactivation of latent infections. This highlights the …

We have previously shown that canine signaling lymphocyte activation molecule (SLAM; also
known as CD150) acts as a cellular receptor for canine distemper virus (CDV). In this study…

Wild-type measles virus (MV) strains use human signaling lymphocyte activation molecule (SLAM)
as a cellular receptor, while vaccine strains such as the Edmonston strain can use …

Interferon (IFN)-α and -β are the main cytokines for innate immune responses against viral
infections. To replicate efficiently in the hosts, viruses have evolved various countermeasures …

SAP is an adaptor mutated in X-linked lymphoproliferative disease. It plays a critical role in
T helper 2 (T H 2) cytokine production. This function was suggested to reflect the capacity of …

This report, the second in a series, describes upgrades of the two-dimensional circulation
model CMS-M2D developed under the Coastal Inlets Research Program CIRP conducted at …