[HTML][HTML] A genetic predictive model for canine hip dysplasia: integration of Genome Wide Association Study (GWAS) and candidate gene approaches
N Bartolomé, S Segarra, M Artieda, O Francino… - PLoS …, 2015 - journals.plos.org
Canine hip dysplasia is one of the most prevalent developmental orthopedic diseases in dogs
worldwide. Unfortunately, the success of eradication programs against this disease based …
worldwide. Unfortunately, the success of eradication programs against this disease based …
ERAP1 polymorphisms and haplotypes are associated with ankylosing spondylitis susceptibility and functional severity in a Spanish population
M Szczypiorska, A Sanchez, N Bartolome… - …, 2011 - academic.oup.com
Objectives. The aim of this study was to assess the involvement of the endoplasmic reticulum
aminopeptidase 1 (ERAP1) gene in AS susceptibility and functional severity in a Spanish …
aminopeptidase 1 (ERAP1) gene in AS susceptibility and functional severity in a Spanish …
Improved prediction of knee osteoarthritis progression by genetic polymorphisms: the Arthrotest Study
…, S Giménez, E Úcar, J Pous, N Bartolomé… - …, 2015 - academic.oup.com
Objective. The aim of this study was to develop a genetic prognostic tool to predict radiographic
progression towards severe disease in primary knee OA (KOA) patients. Methods. This …
progression towards severe disease in primary knee OA (KOA) patients. Methods. This …
Kupffer cell products and interleukin 1? directly promote VLDL secretion and apoB mRNA up-regulation in rodent hepatocytes
N Bartolomé, B Arteta, MJ Martínez, Y Chico… - Innate …, 2008 - journals.sagepub.com
Plasma VLDL accumulation in Gram-negative sepsis is partly ascribed to an increased
hepatic VLDL production driven by pro-inflammatory cytokines. We previously showed that …
hepatic VLDL production driven by pro-inflammatory cytokines. We previously showed that …
Genetic polymorphisms inside and outside the MHC improve prediction of AS radiographic severity in addition to clinical variables
N Bartolome, M Szczypiorska, A Sanchez… - …, 2012 - academic.oup.com
Objective. The aim of this study was to analyse if single nucleotide polymorphisms (SNPs)
inside and outside the MHC region might improve the prediction of radiographic severity in AS…
inside and outside the MHC region might improve the prediction of radiographic severity in AS…
Candidate's single-nucleotide polymorphism predictors of treatment nonresponse to the first anti-TNF inhibitor in ankylosing spondylitis
…, A Sánchez, A Escudero, N Bartolomé… - Rheumatology …, 2014 - Springer
The objective of this study is to identify single-nucleotide polymorphisms (SNPs) predictors
of treatment nonresponse to the first anti-TNF-alpha agent in ankylosing spondylitis (AS). …
of treatment nonresponse to the first anti-TNF-alpha agent in ankylosing spondylitis (AS). …
Biphasic adaptative responses in VLDL metabolism and lipoprotein homeostasis during Gram-negative endotoxemia
N Bartolome, P Aspichueta, MJ Martinez… - Innate …, 2012 - journals.sagepub.com
Dyslipidemia and hepatic overproduction of very low density lipoprotein (VLDL) are hallmarks
of the septic response, yet the underlying mechanisms are not fully defined. We evaluated …
of the septic response, yet the underlying mechanisms are not fully defined. We evaluated …
Upregulation of Apolipoprotein B Secretion, but Not Lipid, by Tumor Necrosis Factor‐α in Rat Hepatocyte Cultures in the Absence of Extracellular Fatty Acids
N Bartolomé, L Rodriguez, MJ Martinez… - Annals of the New …, 2007 - Wiley Online Library
Tumor necrosis factor‐α (TNF‐α) plays a pivotal role in the host response to infection. Rapidly
liberated to the bloodstream, TNF‐α triggers the production of other cytokines and the …
liberated to the bloodstream, TNF‐α triggers the production of other cytokines and the …
[PDF][PDF] Clinical and genetic characteristics of ankylosing spondylitis patients with peripheral arthritis at disease onset
…, M Szczypiorska, N Bartolomé… - Clinical and …, 2019 - clinexprheumatol.org
… Jessica Polo y La Borda, PhD Magdalena Szczypiorska, PhD Nerea Bartolomé, PhD
José Campos, MD Brian J. Flores-Robles, MD Jesús Sanz, MD Cruz Fernández-Espartero …
José Campos, MD Brian J. Flores-Robles, MD Jesús Sanz, MD Cruz Fernández-Espartero …
Isolation and Characterization of the Rat SND p102 Gene Promoter: Putative Role for Nuclear Factor‐Y in Regulation of Transcription
L Rodriguez, N Bartolome, B Ochoa… - Annals of the New …, 2006 - Wiley Online Library
In this work, we report the isolation and characterization of a 1,688‐bp sequence corresponding
to the promoter region of the rat endoplasmic reticulum (ER) cholesterol ester hydrolase …
to the promoter region of the rat endoplasmic reticulum (ER) cholesterol ester hydrolase …