User profiles for Neil A. Segal

Neil Segal

Professor, Rehabilitation Medicine, University of Kansas
Verified email at kumc.edu
Cited by 9928

[HTML][HTML] Nivolumab plus ipilimumab in advanced melanoma

…, NA Rizvi, AM Lesokhin, NH Segal… - … England Journal of …, 2013 - Mass Medical Soc
Background In patients with melanoma, ipilimumab (an antibody against cytotoxic T-lymphocyte–associated
antigen 4 [CTLA-4]) prolongs overall survival, and nivolumab (an antibody …

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

…, P Razavi, CA Klebanoff, R Yaeger, NH Segal… - Nature …, 2019 - nature.com
Immune checkpoint inhibitor (ICI) treatments benefit some patients with metastatic cancers,
but predictive biomarkers are needed. Findings in selected cancer types suggest that tumor …

[HTML][HTML] Immunotherapy in colorectal cancer: rationale, challenges and potential

…, A Cercek, RB Mendelsohn, J Shia, NH Segal… - Nature reviews …, 2019 - nature.com
Following initial successes in melanoma treatment, immunotherapy has rapidly become
established as a major treatment modality for multiple types of solid cancers, including a subset …

[HTML][HTML] Pneumonitis in patients treated with anti–programmed death-1/programmed death ligand 1 therapy

…, J Cunningham, JE Chaft, NH Segal… - Journal of Clinical …, 2017 - ncbi.nlm.nih.gov
Purpose Pneumonitis is an uncommon but potentially fatal toxicity of anti–programmed
death-1 (PD-1)/programmed death ligand 1 (PD-L1) monoclonal antibodies (mAbs). Clinical, …

[HTML][HTML] Organ preservation in patients with rectal adenocarcinoma treated with total neoadjuvant therapy

…, IH Wei, M Widmar, S Lin, NH Segal… - Journal of clinical …, 2022 - ncbi.nlm.nih.gov
PURPOSE Prospective data on the efficacy of a watch-and-wait strategy to achieve organ
preservation in patients with locally advanced rectal cancer treated with total neoadjuvant …

[HTML][HTML] Safety and efficacy of durvalumab (MEDI4736), an anti–programmed cell death ligand-1 immune checkpoint inhibitor, in patients with advanced urothelial …

…, JA Blake-Haskins, A Gupta, NH Segal - Journal of Clinical …, 2016 - ncbi.nlm.nih.gov
Purpose To investigate the safety and efficacy of durvalumab, a human monoclonal antibody
that binds programmed cell death ligand-1 (PD-L1), and the role of PD-L1 expression on …

The effects of Pilates training on flexibility and body composition: an observational study

NA Segal, J Hein, JR Basford - Archives of physical medicine and …, 2004 - Elsevier
Segal NA, Hein J, Basford JR. The effects of Pilates training on flexibility and body composition:
an observational study. Arch Phys Med Rehabil 2004;85:1977–81. OBJECTIVE: To …

[PDF][PDF] Clinical sequencing defines the genomic landscape of metastatic colorectal cancer

…, MTA Donoghue, D You, A Viale, N Kemeny, NH Segal… - Cancer cell, 2018 - cell.com
Metastatic colorectal cancers (mCRCs) are clinically heterogeneous, but the genomic basis
of this variability remains poorly understood. We performed prospective targeted sequencing …

Greater trochanteric pain syndrome: epidemiology and associated factors

NA Segal, DT Felson, JC Torner, Y Zhu… - Archives of physical …, 2007 - Elsevier
… Author links open overlay panel Neil A. Segal MD a , David T. Felson MD b , James C. …
Segal NA, Felson DT, Torner JC, Zhu Y, Curtis JR, Niu J, Nevitt MC, for the Multicenter …

Epitope landscape in breast and colorectal cancer

NH Segal, DW Parsons, KS Peggs, V Velculescu… - Cancer research, 2008 - AACR
The finding that individual cancers contain many mutant genes not present in normal tissues
has prompted considerable interest in the cancer epitope landscape. To further understand …