Nucleic acids are excellent at recognizing complementary sequences through the formation
of Watson− Crick base pairs. Since the base pairing enables the highly selective …

Thermodynamic parameters for prediction of RNA duplex stability are reported. One parameter
for duplex initiation and 10 parameters for helix propagation are derived from enthalpy …

MATERIALS AND METHODS Materials. Sixty-eight oligoribonucleotides and 68 oli-godeoxyribonucleotides
were synthesized chemically on a solid support using phosphoramidite …

The effect of molecular crowding on the structure and stability of biomolecules has become
a subject of increasing interest because it can clarify how biomolecules behave under cell-…

With the goal of being able to create optical devices for the telecommunications industry, we
investigated the effects of 810-nm, femtosecond laser radiation on various glasses. By …

Living cells contain a variety of biomolecules including nucleic acids, proteins,
polysaccharides, and metabolites as well as other soluble and insoluble components. These …

To improve the previous DNA/DNA nearest-neighbor parameters, thermodynamic parameters
(Δ H , Δ S and Δ G ) of 50 DNA/DNA duplexes were measured. Enthalpy change of a helix …

A new curcuminoid, cyclocurcumin (IV), was isolated from the nematocidally active fraction of
turmeric, the rhizome of Curcuma longa, together with three known curcuminoids, curcumin …

We now present the first example in which triplet repeat DNAs adopt the i-motif structure at
neutral pH by molecular crowding. Crowding stabilized the i-motif and the pKa of N3 of …

In the last decade, it has become easy to sequence nucleic acids (48, 69). Where once it
was difficult to sequence a single gene, now whole genomes containing thousands of …