The generic mitogen-activated protein kinases (MAPK) signaling pathway is shared by four
distinct cascades, including the extracellular signal-related kinases (ERK1/2), Jun amino-…

Exosomes are small intracellular membrane-based vesicles with different compositions that
are involved in several biological and pathological processes. The exploitation of exosomes …

… For example, small nonpolar gases such as O 2 , CO 2 , and N 2 , and small polar molecules
such as ethanol cross lipid membranes rapidly. High permeability coefficients have been …

There is increasing evidence for strong genetic influences on athletic performance and for an
evolutionary "trade-off" between performance traits for speed and endurance activities. We …

Fig. 1 Molecular analysis of α-actinin-3 genes and proteins. Indirect immunofluorescence (a−
c) and westernblot analysis (d) of human skeletal muscle (quadriceps muscle biopsy with …

Background Most patients with small-cell lung cancer (SCLC) have extensive-stage disease
at presentation, and prognosis remains poor. Recently, immunotherapy has demonstrated …

… In this paper we report our observations that (1) the PSA concentration determined by
radioimmunoassay (the Yang assay) is proportional to the volume of both the intracapsular and …

The α-actinins are a multigene family of four actin-binding proteins related to dystrophin.
The two skeletal muscle isoforms of α-actinin (ACTN2 and ACTN3) are major structural …

Serum prostate specific antigen was determined (Yang polyclonal radioimmunoassay) in
102 men before hospitalization for radical prostatectomy. Prostate specimens were subjected …

More than a billion humans worldwide are predicted to be completely deficient in the fast
skeletal muscle fiber protein α-actinin-3 owing to homozygosity for a premature stop codon …