[HTML][HTML] Papillon-Lefevre syndrome patient reveals species-dependent requirements for neutrophil defenses
…, SL Dahl, O Østergaard, NH Heegaard… - The Journal of …, 2014 - Am Soc Clin Investig
Papillon-Lefèvre syndrome (PLS) results from mutations that inactivate cysteine protease
cathepsin C (CTSC), which processes a variety of serine proteases considered essential for …
cathepsin C (CTSC), which processes a variety of serine proteases considered essential for …
[HTML][HTML] Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis
…, B Glintborg, ML Hetland, H Locht, NH Heegaard… - BMC Medical …, 2018 - Springer
Background Ankylosing spondylitis (AS) results from the combined effects of susceptibility
genes and environmental factors. Polymorphisms in genes regulating inflammation may …
genes and environmental factors. Polymorphisms in genes regulating inflammation may …
Alpha‐1‐antitrypsin is produced by human neutrophil granulocytes and their precursors and liberated during granule exocytosis
…, O Østergaard, NH Heegaard… - European journal of …, 2011 - Wiley Online Library
… Excess trypsin solution was removed after incubation on ice, and the gel pieces were
covered with 50 mm NH 4 HCO 3 and incubated over night at 37C. Supernatant containing …
covered with 50 mm NH 4 HCO 3 and incubated over night at 37C. Supernatant containing …
[HTML][HTML] Quantitative protein profiling of Chlamydia trachomatis growth forms reveals defense strategies against tryptophan starvation
…, F Follmann, AW Olsen, NH Heegaard… - Molecular & Cellular …, 2016 - ASBMB
Chlamydia trachomatis is one of the most common sexually transmitted bacterial pathogens
in humans. The infection is often asymptomatic and can lead to chronic manifestations. The …
in humans. The infection is often asymptomatic and can lead to chronic manifestations. The …
[HTML][HTML] Large gliadin peptides detected in the pancreas of NOD and healthy mice following oral administration
…, JC Antvorskov, J Larsen, NH Heegaard… - Journal of diabetes …, 2016 - hindawi.com
Gluten promotes type 1 diabetes in nonobese diabetic (NOD) mice and likely also in humans.
In NOD mice and in non-diabetes-prone mice, it induces inflammation in the pancreatic …
In NOD mice and in non-diabetes-prone mice, it induces inflammation in the pancreatic …
IgG glycosylation changes and MBL2 polymorphisms: associations with markers of systemic inflammation and joint destruction in rheumatoid arthritis
…, PM Rudd, E Narvestad, NH Heegaard… - The Journal of …, 2012 - jrheum.org
Objective. To examine whether IgG glycosylation changes and MBL2 genotypes are associated
with systemic inflammation and joint destruction in rheumatoid arthritis (RA). Methods. …
with systemic inflammation and joint destruction in rheumatoid arthritis (RA). Methods. …
Low diagnostic and predictive value of anti-dsDNA antibodies in unselected patients with recent onset of rheumatic symptoms: results from a long-term follow-up …
…, OP Rekvig, L Truedsson, NH Heegaard… - Scandinavian journal …, 2013 - Taylor & Francis
Full article: Low diagnostic and predictive value of anti-dsDNA antibodies in unselected
patients with recent onset of rheumatic symptoms: results from a long-term follow-up …
patients with recent onset of rheumatic symptoms: results from a long-term follow-up …
Serglycin participates in retention of α-defensin in granules during myelopoiesis
A Glenthøj, JB Cowland, NH Heegaard… - Blood, The Journal …, 2011 - ashpublications.org
The mechanism by which proteins are targeted to neutrophil granules is largely unknown. The
intracellular proteoglycan serglycin has been shown to have important functions related to …
intracellular proteoglycan serglycin has been shown to have important functions related to …
Multiple autoimmune manifestations in monoclonal gammopathy of undetermined significance and chronic lymphocytic leukemia.
…, C Krarup, H Schmalbruch, K Thomsen, NH Heegaard… - Leukemia, 1996 - europepmc.org
In 18 cases of monoclonal gammopathy of undetermined significance, MGUS (monoclonal
gammopathy of undetermined significance), admitted for diagnosed or suspected peripheral …
gammopathy of undetermined significance), admitted for diagnosed or suspected peripheral …
Affinity electrophoresis in agarose gels. Theory and some applications.
NH Heegaard, TC Bøg-Hansen - Applied and Theoretical …, 1990 - europepmc.org
Affinity electrophoresis is the electrophoresis of components which interact during the
electrophoresis procedure. Among the numerous modifications of the basic principle, affinity …
electrophoresis procedure. Among the numerous modifications of the basic principle, affinity …