4004 ESC Guidelines label use of medication should be limited to situations where it is in
the patient’s interest to do so, with regard to the quality, safety, and efficacy of care, and only …

• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient’s interest, …

Objective The purpose of the present study was to determine the symptomatology, diagnostic
procedures, and therapeutic strategies of patients with an isolated unilateral absence of a …

Objective Congenital heart disease ( CHD ) is the most common congenital malformation and
causes major morbidity and mortality. Prenatal detection improves the neonatal condition …

… Although the Na + channel blocking efficacy of propranolol has been known for long, a …
particularly more on the late noninactivating Na + current than on the peak Na + current, an effect …

The population of patients with congenital heart disease (CHD) is continuously increasing
with more and more patients reaching adulthood. A significant portion of these young adults …

Background: Cardiac resynchronisation therapy (CRT) is increasingly used in children in a
variety of anatomical and pathophysiological conditions, but published data are scarce. …

Background— Fetal tachyarrhythmia may result in low cardiac output and death. Consequently,
antiarrhythmic treatment is offered in most affected pregnancies. We compared 3 drugs …

Background—Abnormal atrial automaticity in young patients with structurally normal hearts
is often located around the pulmonary veins and in sinus venosus–related parts of the right …

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a familial arrhythmogenic
disorder associated with mutations in the cardiac ryanodine receptor (RyR2) and cardiac …