Hepatitis C virus (HCV) infection is responsible for both hepatic and extra-hepatic disorders (HCV-EHDs);
these latter are correlated on one hand clearly with HCV lymphotropism …

Hepatitis C virus (HCV) is both hepatotrophic and lymphotropic virus that causes liver as
well extrahepatic manifestations including cryoglobulinemic vasculitis, the most frequent and …

The hepatitis C virus (HCV), a linear, single-stranded RNA virus identified in 1989, is a
hepatotropic virus that causes liver cirrhosis and hepatocellular cancer and is a global health …

Autoimmune systemic diseases (ASD) may show impaired immunogenicity to COVID-19
vaccines. Our prospective observational multicenter study aimed to evaluate the …

Hepatitis C virus (HCV)‐associated mixed cryoglobulinemia (MC) vasculitis commonly regresses
upon virus eradication, but conventional therapy with pegylated interferon and ribavirin …

Regression of hepatitis C virus (HCV)–associated lymphoma with interferon (IFN)-based
antiviral treatment supports an etiological link between lymphoma and HCV infection. In addition…

Chronic hepatitis C virus infection causes B cell lymphoproliferative disorders that include
type II mixed cryoglobulinemia and lymphoma. This virus drives the monoclonal expansion …

Severe type II essential mixed cryoglobulinemia (EMC) bears a poor prognosis. Treatment
with corticosteroids and/or cytotoxic drugs infrequently results in long-term remissions, and is …

We have prospectively studied patients with type II cryoglobulinemia since 1985 to assess
the efficacy of treatment with interferon-α at cumulative doses ranging from 234 to 849 MU. In …

OBJECTIVE: Involvement of the central nervous system (CNS) in patients with hepatitis C
virus (HCV) mixed cryoglobulinemia (MC) is rare. The mechanism by which brain lesions are …