Degradation of collagen network and proteoglycan (PG) macromolecules are signs of articular
cartilage degeneration. These changes impair cartilage mechanical function. Effects of …

Quantitative magnetic resonance imaging (MRI) is the most potential non-invasive means
for revealing the structure, composition and pathology of articular cartilage. Here we …

The unknown and variable speed of sound may impair accuracy of the acoustic measurement
of cartilage properties. In this study, relationships between the speed of sound and …

Ultrasound (US) has been suggested as a means for the quantitative detection of early
osteoarthrotic changes in articular cartilage. In this study, the ability of quantitative US 2-D …

Previous studies have suggested that quantitative ultrasound imaging could sensitively
diagnose degeneration of the articular surface and changes in the subchondral bone during the …

High-frequency ultrasound (US) measurements may provide means for the quantification of
articular cartilage quality. Bovine patellar cartilage samples (n = 32) at various degenerative …

We have earlier developed a handheld ultrasound indentation instrument for the diagnosis of
articular cartilage degeneration. In ultrasound indentation, cartilage is compressed with the …

Background: The combined use of high-frequency ultrasound and mechanical indentation
has been suggested for the evaluation of cartilage integrity. In this study, we investigated the …

Softening of articular cartilage, mainly attributable to deterioration of superficial collagen
network and depletion of proteoglycans, is a sign of incipient osteoarthrosis. Early diagnosis of …

Cellular responses to mechanical stimuli are influenced by the mechanical properties of
cells and the surrounding tissue matrix. Cells exhibit viscoelastic behavior in response to an …