Phenotypic characterization of osteoblasts from the sclerotic zones of osteoarthritic subchondral bone
C Sanchez, MA Deberg, A Bellahcène… - … : Official Journal of …, 2008 - Wiley Online Library
Objective To determine the phenotype of osteoblasts from the sclerotic zones of human
osteoarthritic (OA) subchondral bone. Methods Human osteoblasts were isolated from sclerotic …
osteoarthritic (OA) subchondral bone. Methods Human osteoblasts were isolated from sclerotic …
Avocado/soybean unsaponifiables increase aggrecan synthesis and reduce catabolic and proinflammatory mediator production by human osteoarthritic chondrocytes.
YE Henrotin, C Sanchez, MA Deberg… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: To investigate the effects of avocado (A)/soybean (S) unsaponifiables on the
metabolism of human osteoarthritic (OA) chondrocytes cultured in alginate beads over 12 days…
metabolism of human osteoarthritic (OA) chondrocytes cultured in alginate beads over 12 days…
Effects of rhein on human articular chondrocytes in alginate beads
C Sanchez, M Mathy-Hartert, MA Deberg… - Biochemical …, 2003 - Elsevier
This study was designed to investigate the effects of rhein, the active metabolite of
diacerhein, on the metabolic functions of human chondrocytes cultured in alginate beads. …
diacerhein, on the metabolic functions of human chondrocytes cultured in alginate beads. …
Avocado/soybean unsaponifiables prevent the inhibitory effect of osteoarthritic subchondral osteoblasts on aggrecan and type II collagen synthesis by chondrocytes.
YE Henrotin, MA Deberg, JM Crielaard… - The Journal of …, 2006 - jrheum.org
OBJECTIVE: To determine the effects of avocado/soybean unsaponifiables (ASU) on
osteoblast-induced dysregulation of chondrocyte metabolism. METHODS: Human chondrocytes …
osteoblast-induced dysregulation of chondrocyte metabolism. METHODS: Human chondrocytes …
[HTML][HTML] Differential regulation of chondrocyte metabolism by oncostatin M and interleukin-6
C Sanchez, MA Deberg, S Burton, P Devel… - Osteoarthritis and …, 2004 - Elsevier
OBJECTIVE: To determine the effects of interleukin (IL)-6 and oncostatin M (OSM) added
separately or in combination with IL-1β on human osteoarthritic (OA) chondrocytes in alginate …
separately or in combination with IL-1β on human osteoarthritic (OA) chondrocytes in alginate …
[HTML][HTML] New serum biochemical markers (Coll 2-1 and Coll 2-1 NO2) for studying oxidative-related type II collagen network degradation in patients with osteoarthritis …
M Deberg, A Labasse, S Christgau, P Cloos… - Osteoarthritis and …, 2005 - Elsevier
OBJECTIVE: Protein nitration is a prominent feature of inflammatory processes in the joint.
We have developed immunoassays specific for a peptide of the α-helical region of type II …
We have developed immunoassays specific for a peptide of the α-helical region of type II …
Fibulin 3 peptides Fib3‐1 and Fib3‐2 are potential biomarkers of osteoarthritis
…, JE Dubuc, E De Pauw, M Deberg - Arthritis & …, 2012 - Wiley Online Library
Objective This study was undertaken to identify new biomarkers of osteoarthritis (OA) by
proteomics analysis and to develop specific immunoassays to detect and quantify them. …
proteomics analysis and to develop specific immunoassays to detect and quantify them. …
[HTML][HTML] Collagen fibril disruption occurs early in primary guinea pig knee osteoarthritis
JL Huebner, JM Williams, M Deberg, Y Henrotin… - Osteoarthritis and …, 2010 - Elsevier
OBJECTIVE: A major barrier inhibiting the discovery of structural modifying agents for osteoarthritis
(OA) is an incomplete understanding of early disease events. Herein, we investigated …
(OA) is an incomplete understanding of early disease events. Herein, we investigated …
[HTML][HTML] Application for proteomic techniques in studying osteoarthritis: a review
M Gharbi, M Deberg, Y Henrotin - Frontiers in physiology, 2011 - frontiersin.org
After the genomic era, proteomic corresponds to a wide variety of techniques that study the
protein content of cells, tissue, or organism and that allow the isolation of protein of interest. It …
protein content of cells, tissue, or organism and that allow the isolation of protein of interest. It …
Relationship between biochemical markers and radiographic scores in the evaluation of the osteoarticular status of Warmblood stallions
…, J Detilleux, S Grulke, M Deberg… - Research in veterinary …, 2009 - Elsevier
Establishing the osteoarticular status of the horse is often performed by means of radiological
screening of the animals. Widespread blood sampling could reveal to be an interesting …
screening of the animals. Widespread blood sampling could reveal to be an interesting …