BACKGROUND: The exact pathogenesis of the pediatric disorder periodic fever, aphthous
stomatitis, pharyngitis, cervical adenitis (PFAPA) syndrome is unknown. OBJECTIVES: We …

The syndrome of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA
syndrome) is the most common cause of periodic fever in childhood. The current …

We aimed to compare physical activity level and cardiorespiratory fitness in children with
different chronic diseases, such as type 1 diabetes mellitus (T1DM), obesity (OB) and juvenile …

Background Interleukin-1 is pivotal in the pathogenesis of systemic juvenile idiopathic arthritis
(JIA). We assessed the efficacy and safety of canakinumab, a selective, fully human, anti–…

By the addition of metal and oxide particles to plastics, thermal transport properties, heat
capacity, and density of polymers can be varied systematically. Composites samples of …

We present a system for automatic reassembly of broken 3D solids. Given as input 3D digital
models of the broken fragments, we analyze the geometry of the fracture surfaces to find a …

Objective To evaluate the response to treatment of autoinflammatory diseases from an
international registry and an up-to-date literature review. Methods The response to treatment was …

Background Familial Mediterranean fever, mevalonate kinase deficiency (also known as the
hyperimmunoglobulinemia D syndrome), and the tumor necrosis factor receptor–associated …

PFAPA syndrome is the most common autoinflammatory syndrome in children from Western
countries. In spite of its strong familial clustering, its genetic basis and inheritance pattern …

Background Different diagnostic and classification criteria are available for hereditary
recurrent fevers (HRF)—familial Mediterranean fever (FMF), tumour necrosis factor receptor-…