The airways, a novel route for delivering monoclonal antibodies to treat lung tumors

…, DH Douvin, J Hureaux, Y Courty, M De Monte… - Pharmaceutical …, 2011 - Springer
Purpose Lung cancer is the leading cause of cancer-related death worldwide. The efficacy
of current systemic treatments is limited, with major side effects and only modest survival …

KLK5 and KLK7, two members of the human tissue kallikrein family, are differentially expressed in lung cancer

C Planque, M de Monte, S Guyetant, J Rollin… - Biochemical and …, 2005 - Elsevier
Emerging data indicate that serine proteases of the kallikrein family (KLK) are implicated in
various human diseases, including carcinoma; however, kallikrein gene expression has …

Ultra-early weaning in piglets results in low serum IgA concentration and IL17 mRNA expression

B Levast, M de Monte, C Chevaleyre, S Melo… - Veterinary immunology …, 2010 - Elsevier
In pigs raised for meat production, weaning is a critical period because of related physiological
perturbations and negative consequences on performance. Previous studies have shown …

Relationship between occupational risk factors and severity markers of systemic sclerosis.

J Magnant, M de Monte, JL Guilmot… - The Journal of …, 2005 - jrheum.org
OBJECTIVE: To investigate a potential association between occupational risk factors and
severity markers of systemic sclerosis (SSc) defined by diffuse cutaneous extent, pulmonary …

[HTML][HTML] Aerosol deposition in neonatal ventilation

JC Dubus, L Vecellio, M De Monte, JB Fink… - Pediatric …, 2005 - nature.com
Lung deposition of inhaled drugs in ventilated neonates has been studied in models of
questionable relevance. With conventional nebulizers, pulmonary deposition has been limited to …

[HTML][HTML] Particle Deposition in a Child Respiratory Tract Model: In Vivo Regional Deposition of Fine and Ultrafine Aerosols in Baboons

…, M Durand, J Avet, D Le Pennec, M De Monte… - PloS one, 2014 - journals.plos.org
To relate exposure to adverse health effects, it is necessary to know where particles in the
submicron range deposit in the respiratory tract. The possibly higher vulnerability of children …

Competition between elastase and related proteases from human neutrophil for binding to α1-protease inhibitor

…, P Poutrain, E Hazouard, M de Monte… - American journal of …, 2005 - atsjournals.org
The protease–antiprotease imbalance that is characteristic of most inflammatory lung
disorders depends on the spatial-temporal regulation of active inhibitor and protease …

[HTML][HTML] Relationship between ozone and temperature during the 2003 heat wave in France: consequences for health data analysis

SA Lacour, M De Monte, P Diot, J Brocca, N Veron… - BMC Public Health, 2006 - Springer
Background PAPRICA is a research program designed to estimate the impact on the health
of patients with chronic respiratory insufficiency of a prevention strategy based on notification …

Evaluation of lung tolerance of ethanol, propylene glycol, and sorbitan monooleate as solvents in medical aerosols

…, F Gauthier, P Diot, M de Monte - Journal of aerosol …, 2010 - liebertpub.com
Background: Aerosol therapy is an expanding technique allowing administration of drugs
acting locally in the bronchial tree and lungs or acting systemically after absorption through the …

Exploring the fate of inhaled monoclonal antibody in the lung parenchyma by microdialysis

…, R Respaud, D Marchand, J Montharu, M De Monte… - MAbs, 2019 - Taylor & Francis
Therapeutic antibodies (Abs) are emerging as major drugs to treat respiratory diseases, and
inhalation may provide substantial benefits for their delivery. Understanding the behavior of …