Background Oral contraceptives are rarely prescribed for women with systemic lupus
erythematosus, because of concern about potential negative side effects. In this double-blind, …

Background and aims We studied damage accrual and factors determining development
and progression of damage in an international cohort of systemic lupus erythematosus (SLE) …

Objective Analysis of peripheral B cell subsets in patients with systemic lupus erythematosus
(SLE) has provided evidence of specific alterations, such as an expansion of CD27++ …

The inappropriate expansion and activation of autoreactive memory B cells and plasmablasts
contributes to loss of self-tolerance in systemic lupus erythematosus (SLE). Defects in the …

Objective There is a need to determine which response measures in lupus nephritis trials
are most predictive of good long‐term renal function. We used data from the Euro‐Lupus …

Increased risk of premature cardiovascular disease (CVD) is well recognized in systemic lupus
erythematosus (SLE). Aberrant type I-Interferon (IFN)-neutrophil interactions contribute to …

Objective To understand the effects of long‐term BLyS inhibition in human systemic lupus
erythematosus (SLE). Methods Seventeen patients with SLE who were enrolled in a clinical …

Nephrophilic autoantibodies dominate the seroprofile in lupus, but their fine specificities
remain ill defined. We constructed a multiplexed proteome microarray bearing about 30 …

Background Excessive activity of dendritic cells (DCs) is postulated as a central disease
mechanism in Systemic Lupus Erythematosus (SLE). Vitamin D is known to reduce …

Introduction TNF-like weak inducer of apoptosis (TWEAK) has been implicated as a mediator
of chronic inflammatory processes via prolonged activation of the NF-κB pathway in several …