Synovial fluid profile at the time of anterior cruciate ligament reconstruction and its association with cartilage matrix composition 3 years after surgery

…, JL Huebner, TV Stabler, M Tanaka… - … American journal of …, 2018 - journals.sagepub.com
Background: Anterior cruciate ligament tears can lead to posttraumatic osteoarthritis. In
addition to biomechanical factors, changes in biochemical profiles within the knee joint after …

Abnormal biomechanics at 6 months are associated with cartilage degeneration at 3 years after anterior cruciate ligament reconstruction

T Shimizu, MA Samaan, MS Tanaka, V Pedoia… - … : The Journal of …, 2019 - Elsevier
Purpose To investigate the changes in landing biomechanics over a 3-year period and their
correlation with cartilage degenerative changes in the medial tibiofemoral joint of the knee …

[HTML][HTML] Multi-vendor multi-site T1ρ and T2 quantification of knee cartilage

…, W Shin, CS Winalski, N Obuchowski, M Tanaka… - Osteoarthritis and …, 2020 - Elsevier
Objective To develop 3D T 1ρ and T 2 imaging based on the same sequence structure on
MR systems from multiple vendors, and to evaluate intra-site repeatability and inter-site inter-…

Prediction of local fixed charge density loss in cartilage following ACL injury and reconstruction: a computational proof‐of‐concept study with MRI follow‐up

…, P Bolcos, A Mohammadi, MS Tanaka… - Journal of …, 2021 - Wiley Online Library
The purpose of this proof‐of‐concept study was to develop three‐dimensional patient‐specific
mechanobiological knee joint models to simulate alterations in the fixed charged density (…

[HTML][HTML] Comparison between kinetic and kinetic-kinematic driven knee joint finite element models

…, A Mohammadi, M Ebrahimi, MS Tanaka… - Scientific reports, 2018 - nature.com
Use of knee joint finite element models for diagnostic purposes is challenging due to their
complexity. Therefore, simpler models are needed for studies where a high number of patients …

[HTML][HTML] Infrapatellar fat pad abnormalities are associated with a higher inflammatory synovial fluid cytokine profile in young adults following ACL tear

…, K Mamoto, K Amano, B Eck, M Tanaka… - Osteoarthritis and …, 2020 - Elsevier
Objective To evaluate the degree of knee fat pad abnormalities after acute anterior cruciate
ligament (ACL) tear via magnetic resonance fat pad scoring and to assess cross-sectionally …

[HTML][HTML] Assessment of 3-month changes in bone microstructure under anti-TNFα therapy in patients with rheumatoid arthritis using high-resolution peripheral …

T Shimizu, HJ Choi, U Heilmeier, M Tanaka… - Arthritis research & …, 2017 - Springer
Background Although one study showed minimal progression of erosions in patients with
rheumatoid arthritis (RA) one year after TNFα inhibition therapy, no studies have investigated …

[HTML][HTML] 3D bone-shape changes and their correlations with cartilage T1ρ and T2 relaxation times and patient-reported outcomes over 3-years after ACL …

Q Zhong, V Pedoia, M Tanaka, J Neumann… - Osteoarthritis and …, 2019 - Elsevier
Purpose (1) To identify bone-shape changes from baseline to 3-years after anterior cruciate
ligament reconstruction (ACLR). (2) to assess association between changes in bone-shape …

[HTML][HTML] Identification of locations susceptible to osteoarthritis in patients with anterior cruciate ligament reconstruction: Combining knee joint computational modelling …

PO Bolcos, ME Mononen, MS Tanaka, M Yang… - Clinical …, 2020 - Elsevier
Background Finite element modelling can be used to evaluate altered loading conditions
and failure locations in knee joint tissues. One limitation of this modelling approach has been …

Shear strain and inflammation‐induced fixed charge density loss in the knee joint cartilage following ACL injury and reconstruction: A computational study

…, JP Kosonen, MS Tanaka… - Journal of …, 2022 - Wiley Online Library
Excessive tissue deformation near cartilage lesions and acute inflammation within the knee
joint after anterior cruciate ligament (ACL) rupture and reconstruction surgery accelerate the …