Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients
S Kotake, N Udagawa, M Hakoda… - … : Official Journal of …, 2001 - Wiley Online Library
Objective To elucidate the direct role of human T cells in the induction of osteoclastogenesis
in rheumatoid arthritis (RA), by studying human monocytes and the pathogenetic roles of …
in rheumatoid arthritis (RA), by studying human monocytes and the pathogenetic roles of …
Detection of soluble tumor-associated antigens in sera and effusions using novel monoclonal antibodies, KL-3 and KL-6, against lung adenocarcinoma
…, M Akiyama, S Kyoizumi, M Hakoda… - Japanese Journal of …, 1988 - academic.oup.com
Two novel monoclonal antibodies, KL-3 (IgM) and KL-6 (IgG 1 ), which can detect soluble
antigens in sera and effusions (molecular weights > 1,000 K) were produced against human …
antigens in sera and effusions (molecular weights > 1,000 K) were produced against human …
Long-term effects of radiation dose on inflammatory markers in atomic bomb survivors
…, Y Kusunoki, I Hayashi, F Kasagi, M Hakoda… - The American journal …, 2005 - amjmed.com
Results There were no significant differences in age, sex, body mass index, or current smoking
among the four groups (Table 1). Interferon levels and the erythrocyte sedimentation rate …
among the four groups (Table 1). Interferon levels and the erythrocyte sedimentation rate …
Optimal range of serum urate concentrations to minimize risk of gouty attacks during anti-hyperuricemic treatment
H Yamanaka, R Togashi, M Hakoda, C Terai… - Purine and Pyrimidine …, 1998 - Springer
To find an optimal range of urate concentrations wherein the risk of attacks during the initial
6 months of treatment is minimized, data from 350 gouty patients treated with …
6 months of treatment is minimized, data from 350 gouty patients treated with …
[HTML][HTML] Urine alkalization facilitates uric acid excretion
A Kanbara, M Hakoda, I Seyama - Nutrition journal, 2010 - Springer
Background Increase in the incidence of hyperuricemia associated with gout as well as
hypertension, renal diseases and cardiovascular diseases has been a public health concern. We …
hypertension, renal diseases and cardiovascular diseases has been a public health concern. We …
KL-6 as a novel serum marker for interstitial pneumonia associated with collagen diseases.
H Nakajima, M Harigai, M Hara, M Hakoda… - The Journal of …, 2000 - europepmc.org
KL-6 as a novel serum marker for interstitial pneumonia associated with collagen diseases. -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …
[HTML][HTML] Clinical practice guideline for renal hypouricemia
…, H Matsuo, A Ohtahara, K Ogino, M Hakoda… - Human Cell, 2019 - Springer
Renal hypouricemia (RHUC) is a disease caused by dysfunction of renal urate reabsorption
transporters; however, diagnostic guidance and guidelines for RHUC have been lacking, …
transporters; however, diagnostic guidance and guidelines for RHUC have been lacking, …
Serum uric acid concentration as a risk factor for cardiovascular mortality: a longterm cohort study of atomic bomb survivors.
M Hakoda, N Masunari, M Yamada, S Fujiwara… - The Journal of …, 2005 - jrheum.org
OBJECTIVE: To elucidate the association of serum uric acid concentration with cardiovascular
mortality risk. METHODS: Serum uric acid level measured from 1966 through 1970 in …
mortality risk. METHODS: Serum uric acid level measured from 1966 through 1970 in …
Associations between HLA-DRB1, RANK, RANKL, OPG, and IL-17 genotypes and disease severity phenotypes in Japanese patients with early rheumatoid …
T Furuya, M Hakoda, N Ichikawa, K Higami… - Clinical …, 2007 - Springer
We examined associations between human leukocyte antigen DRB1 (HLA-DRB1) shared
epitope (SE), receptor activator of nuclear factor-kappaB (RANK), RANK ligand (RANKL), …
epitope (SE), receptor activator of nuclear factor-kappaB (RANK), RANK ligand (RANKL), …
Immunogenetic features in 120 Japanese patients with idiopathic inflammatory myopathy.
T Furuya, M Hakoda, N Tsuchiya, S Kotake… - The Journal of …, 2004 - jrheum.org
OBJECTIVE: To examine the role of HLA-DRB1 and tumor necrosis factor (TNF) promoter
genotypes in the development and the autoantibody profiles of idiopathic inflammatory …
genotypes in the development and the autoantibody profiles of idiopathic inflammatory …