User profiles for Mark Siedner

Mark J. Siedner

Associate Professor of Medicine, Harvard Medical School
Verified email at partners.org
Cited by 9665

[HTML][HTML] Social distancing to slow the US COVID-19 epidemic: Longitudinal pretest–posttest comparison group study

MJ Siedner, G Harling, Z Reynolds, RF Gilbert… - PLoS …, 2020 - journals.plos.org
Background Social distancing measures to address the US coronavirus disease 2019 (COVID-19)
epidemic may have notable health and social impacts. Methods and findings We …

Trends in CD4 count at presentation to care and treatment initiation in sub-Saharan Africa, 2002–2013: a meta-analysis

MJ Siedner, CK Ng, IV Bassett, IT Katz… - Clinical infectious …, 2015 - academic.oup.com
Background. Both population- and individual-level benefits of antiretroviral therapy (ART)
for human immunodeficiency virus (HIV) are contingent on early diagnosis and initiation of …

[HTML][HTML] Duration of shedding of culturable virus in SARS-CoV-2 Omicron (BA. 1) infection

…, JM Vyas, JZ Li, JE Lemieux, MJ Siedner… - … England Journal of …, 2022 - Mass Medical Soc
Siedner, MD, MPH … Goldberg, JZ Li, Lemieux, Siedner, and Barczak) from the
Massachusetts Consortium for Pathogen Readiness , a grant (to Dr. Vyas) from the …

Impact of geographic and transportation-related barriers on HIV outcomes in sub-Saharan Africa: a systematic review

AJ Lankowski, MJ Siedner, DR Bangsberg, AC Tsai - AIDS and Behavior, 2014 - Springer
Difficulty obtaining reliable transportation to clinic is frequently cited as a barrier to HIV care
in sub-Saharan Africa (SSA). Numerous studies have sought to characterize the impact of …

Access to primary healthcare during lockdown measures for COVID-19 in rural South Africa: an interrupted time series analysis

MJ Siedner, JD Kraemer, MJ Meyer, G Harling… - BMJ open, 2020 - bmjopen.bmj.com
Objectives We evaluated whether implementation of lockdown orders in South Africa affected
ambulatory clinic visitation in rural Kwa-Zulu Natal (KZN). Design Observational cohort …

[PDF][PDF] Altered virome and bacterial microbiome in human immunodeficiency virus-associated acquired immunodeficiency syndrome

…, JN Martin, PW Hunt, DR Bangsberg, MJ Siedner… - Cell host & …, 2016 - cell.com
Human immunodeficiency virus (HIV) infection is associated with increased intestinal
translocation of microbial products and enteropathy as well as alterations in gut bacterial …

[PDF][PDF] The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites

…, JC Valderramos, C Vilcheze, M Siedner… - Cell host & …, 2008 - cell.com
The fatty acid synthesis type II pathway has received considerable interest as a candidate
therapeutic target in Plasmodium falciparum asexual blood-stage infections. This apicoplast-…

Immunologic biomarkers, morbidity, and mortality in treated HIV infection

PW Hunt, SA Lee, MJ Siedner - The Journal of infectious …, 2016 - academic.oup.com
Despite marked improvements in the modern treatment era, human immunodeficiency virus
(HIV)–infected individuals, particularly those who initiated antiretroviral therapy (ART) at …

Characterization of virologic rebound following nirmatrelvir-ritonavir treatment for coronavirus disease 2019 (COVID-19)

…, JE Lemieux, AK Barczak, MJ Siedner - Clinical Infectious …, 2023 - academic.oup.com
We enrolled 7 individuals with recurrent symptoms or antigen test conversion following
nirmatrelvir-ritonavir treatment. High viral loads (median 6.1 log 10 copies/mL) were detected …

Circulating clonotypic B cells in classic Hodgkin lymphoma

…, JM Gerber, LL Gellert, M Siedner… - Blood, The Journal …, 2009 - ashpublications.org
Although Hodgkin and Reed-Sternberg (HRS) cells are B lymphoid cells, they are unlike any
normal cells of that lineage. Moreover, the limited proliferative potential of HRS cells belies …