INTRODUCTION: The treatment of the fibromyalgia syndrome (FMS) is not standardized and
often ineffective, and the course of disease progression is unpredictable. OBJECTIVES: To …

OBJECTIVE: In the dynamic organization of sleep, cyclic alternating pattern (CAP) expresses
a condition of instability of the level of vigilance that manifests the brain's fatigue in …

Studies on autoantibody production in patients treated with tumor necrosis factor-α (TNF-α)
inhibitors reported contradictory results. We investigated in a prospective study the efficacy of …

Objectives: The aim of this study was to assess thyroid function as well as the prevalence and
clinical value of anti-thyroid antibodies in patients with rheumatoid arthritis (RA). Methods: …

Tumour necrosis factor-alpha (TNF-α) is a pro-inflammatory cytokine produced by many cell
types (blood monocytes, macrophages, mast cells and endothelial cells), that play a key role …

Neutrophils are known to be targets for the biological activity of tumour necrosis factor (TNF)-α
in the pathogenensis of rheumatoid arthritis (RA). Therefore, these cells may be among …

Background: Rheumatoid arthritis (RA) is frequently associated with organ or non-organ-specific
autoantibodies or overt autoimmune disorders. Aim of our study was to assess the …

Objective: To investigate the prevalence of antipolymer antibody (APA) in patients with
fibromyalgia (FM) and to examine its association with FM severity symptoms. Methods: The study …

Hyperhomocysteinemia (HH) has been associated with cardiovascular and autoimmune
diseases and oxidative cell damage. Myelodysplastic syndromes (MDS) are associated with …

Publisher Summary Rheumatoid arthritis (RA) is a chronic inflammatory systemic disorder of
unknown etiology. This disease affects about 0.5–1% of the population worldwide, most …