DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

…, D Gell, GCM Smith, H Zhang, N Divecha, MA Connelly… - Cell, 1995 - cell.com
DNA-dependent protein kinase (DNA-PK), which is involved in DNA double-stranded break
repair and V (D) J recombination, comprises a DNA-targeting component called Ku and an-…

[HTML][HTML] High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by …

…, S Swarnakar, P Monzo, SM Klein, MA Connelly… - Journal of Biological …, 2000 - ASBMB
The role of high density lipoprotein (HDL) phospholipid in scavenger receptor BI (SR-BI)-mediated
free cholesterol flux was examined by manipulating HDL 3 phosphatidylcholine and …

GlycA: a composite nuclear magnetic resonance biomarker of systemic inflammation

…, J Wolak-Dinsmore, MA Connelly… - Clinical …, 2015 - academic.oup.com
BACKGROUND Nuclear magnetic resonance (NMR) spectra of serum obtained under
quantitative conditions for lipoprotein particle analyses contain additional signals that could …

[HTML][HTML] Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface

M de la Llera-Moya, GH Rothblat, MA Connelly… - Journal of lipid …, 1999 - ASBMB
In addition to its effect on high density lipoprotein (HDL) cholesteryl ester (CE) uptake,
scavenger receptor BI (SR-BI) was recently reported to stimulate free cholesterol (FC) flux from …

[HTML][HTML] Comparison of class B scavenger receptors, CD36 and scavenger receptor BI (SR-BI), shows that both receptors mediate high density lipoprotein-cholesteryl …

MA Connelly, SM Klein, S Azhar, NA Abumrad… - Journal of Biological …, 1999 - ASBMB
Scavenger receptor BI (SR-BI) mediates the selective uptake of high density lipoprotein (HDL)
cholesteryl ester (CE), a process by which HDL CE is taken into the cell without …

[HTML][HTML] GlycA, a novel biomarker of systemic inflammation and cardiovascular disease risk

MA Connelly, JD Otvos, I Shalaurova… - Journal of translational …, 2017 - Springer
Background GlycA is a novel spectroscopic marker of systemic inflammation with low intra-individual
variability and other attributes favoring its clinical use in patients with chronic …

Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile

…, JS Qi, J McCrea, S Klein, MA Connelly… - Human molecular …, 2011 - academic.oup.com
Membrane CD36 functions in the uptake of fatty acids (FAs), oxidized lipoproteins and in signal
transduction after binding these ligands. In rodents, CD36 is implicated in abnormal lipid …

Scavenger receptor Bl and cholesterol trafficking

DL Williams, MA Connelly, RE Temel… - Current opinion in …, 1999 - journals.lww.com
Scavenger receptor Bl (SR-BI) mediates the selective uptake of HDL cholesteryl ester into
steroidogenic cells and the liver and is a major determinant of the plasma HDL concentration …

[HTML][HTML] Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor–BI mediate HDL-initiated signaling

…, IS Yuhanna, YL Marcel, MA Connelly… - The Journal of …, 2005 - Am Soc Clin Investig
The binding of HDL to scavenger receptor–BI (SR-BI) mediates cholesterol movement. HDL
also induces multiple cellular signals, which in endothelium occur through SR-BI and …

Lipoprotein Insulin Resistance Index: a lipoprotein particle–derived measure of insulin resistance

I Shalaurova, MA Connelly, WT Garvey… - … syndrome and related …, 2014 - liebertpub.com
Background: Lipoprotein particle sizes and concentrations are characteristically altered in
patients with insulin resistance (IR) or type 2 diabetes mellitus (T2DM). This study assessed …