Genome Sequence of Aedes aegypti, a Major Arbovirus Vector

…, Q Zhao, Y Zhao, CA Hill, AS Raikhel, MB Soares… - Science, 2007 - science.org
We present a draft sequence of the genome of Aedes aegypti, the primary vector for yellow
fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the …

Construction and characterization of a normalized cDNA library.

MB Soares, MF Bonaldo, P Jelene… - Proceedings of the …, 1994 - National Acad Sciences
We have developed a simple procedure based on reassociation kinetics that can reduce
effectively the high variation in abundance among the clones of a cDNA library that represent …

[HTML][HTML] The P4 health spectrum–a predictive, preventive, personalized and participatory continuum for promoting healthspan

…, BS McEwen, MB Soares… - Progress in …, 2017 - journals.lww.com
Chronic diseases (ie, noncommunicable diseases), mainly cardiovascular disease, cancer,
respiratory diseases and type-2-diabetes, are now the leading cause of death, disability and …

[HTML][HTML] Insights into a dinoflagellate genome through expressed sequence tag analysis

JD Hackett, TE Scheetz, HS Yoon, MB Soares… - BMC genomics, 2005 - Springer
Background Dinoflagellates are important marine primary producers and grazers and cause
toxic "red tides". These taxa are characterized by many unique features such as immense …

[HTML][HTML] Identification of differentially expressed microRNAs in osteosarcoma

…, PM Chou, MF Bonaldo, EF Vanin, MB Soares - Sarcoma, 2011 - hindawi.com
A limited number of reports have investigated the role of microRNAs in osteosarcoma. In this
study, we performed miRNA expression profiling of osteosarcoma cell lines, tumor samples, …

[HTML][HTML] Identification of microRNAs as potential prognostic markers in ependymoma

…, D Wang, S Goldman, T Tomita, MB Soares - PloS one, 2011 - journals.plos.org
Introduction We have examined expression of microRNAs (miRNAs) in ependymomas to
identify molecular markers of value for clinical management. miRNAs are non-coding RNAs …

Genome-wide quantitative assessment of variation in DNA methylation patterns

…, S Goldman, T Tomita, MB Soares - Nucleic acids …, 2011 - academic.oup.com
Genomic DNA methylation contributes substantively to transcriptional regulations that
underlie mammalian development and cellular differentiation. Much effort has been made to …

[HTML][HTML] Folic acid remodels chromatin on Hes1 and Neurog2 promoters during caudal neural tube development

…, DG McLone, T Tomita, MB Soares… - Journal of Biological …, 2010 - ASBMB
The mechanism(s) behind folate rescue of neural tube closure are not well understood. In
this study we show that maternal intake of folate prior to conception reverses the proliferation …

Use of laser-capture microdissection for the identification of marker genes for the ventromedial hypothalamic nucleus

…, N Socci, A Viale, TM Harris, MB Soares… - Journal of …, 2005 - Soc Neuroscience
The ventromedial hypothalamic nucleus (VMH) plays an important role in the control of feeding
and energy homeostasis. In contrast to other hypothalamic nuclei that are also known to …

High-throughput sequence-based epigenomic analysis of Alu repeats in human cerebellum

…, S Goldman, T Tomita, MB Soares - Nucleic acids …, 2009 - academic.oup.com
DNA methylation, the only known covalent modification of mammalian DNA, occurs primarily
in CpG dinucleotides. 51% of CpGs in the human genome reside within repeats, and 25% …