Interleukin 17A: toward a new understanding of psoriasis pathogenesis

CW Lynde, Y Poulin, R Vender, M Bourcier… - Journal of the American …, 2014 - Elsevier
Molecular and cellular understanding of psoriasis pathogenesis has evolved considerably
over the last 30 years beginning in the early 1980s when psoriasis was thought to be a skin …

Evidence that a neutrophil–keratinocyte crosstalk is an early target of IL‐17A inhibition in psoriasis

…, JH Tu, R Bissonnette, M Bourcier… - Experimental …, 2015 - Wiley Online Library
The response of psoriasis to antibodies targeting the interleukin ( IL )‐23/ IL ‐17A pathway
suggests a prominent role of T‐helper type‐17 (Th17) cells in this disease. We examined the …

[HTML][HTML] Recategorization of psoriasis severity: Delphi consensus from the International Psoriasis Council

…, AB Kimball, J Barker, A Blauvelt, M Bourcier… - Journal of the American …, 2020 - Elsevier
Background Psoriasis severity categories have been important tools for clinicians to use in
treatment decisions as well as to determine eligibility criteria for clinical studies. However, …

Assessment of the long-term safety and effectiveness of etanercept for the treatment of psoriasis in an adult population

KA Papp, Y Poulin, R Bissonnette, M Bourcier… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Etanercept is well tolerated and effective in moderate to severe plaque
psoriasis. However, effectiveness and safety data beyond 2.5 years have not been reported. …

[HTML][HTML] Clinical goals and barriers to effective psoriasis care

…, JM van der Walt, AW Armstrong, M Bourcier… - Dermatology and …, 2019 - Springer
Engaging global key opinion leaders, the International Psoriasis Council (IPC) held a day-long
roundtable discussion with the primary purpose to discuss the treatment goals of …

Psychosocial burden and other impacts of rosacea on patients' quality of life

E Oussedik, M Bourcier, J Tan - Dermatologic clinics, 2018 - derm.theclinics.com
Rosacea is a common and chronic skin disorder characterized by persistent redness on the
convex surfaces of the face in addition to a spectrum of facial clinical features including …

Immune response to pneumococcus and tetanus toxoid in patients with moderate-to-severe psoriasis following long-term ustekinumab use.

…, RG Langley, KA Papp, M Bourcier… - Journal of Drugs in …, 2013 - europepmc.org
Background Little is known about the impact of long-term use of immunosuppressive agents
on immune response. Objectives Assess the impact of continuous maintenance …

Understanding genital warts: epidemiology, pathogenesis, and burden of disease of human papillomavirus

…, C Lynde, R Vender, M Bourcier - Journal of cutaneous …, 2013 - journals.sagepub.com
As the most commonly sexually transmitted disease worldwide, human papillomavirus (HPV)
infections are associated with significant morbidity and mortality. HPV infections most …

[HTML][HTML] Systematic review on the efficacy and safety of oral janus kinase inhibitors for the treatment of atopic dermatitis

M Le, M Berman-Rosa, FM Ghazawi, M Bourcier… - Frontiers in …, 2021 - frontiersin.org
Background: Atopic dermatitis is a chronic, relapsing and remitting disease that can be
difficult to treat despite a recently approved biologic therapy targeting IL-4/IL-13 receptor. Oral …

Approach to the management of patients with hidradenitis suppurativa: a consensus document

…, C Lynde, R Alhusayen, M Bourcier… - Journal of …, 2017 - journals.sagepub.com
Marc Bourcier has served as consultant for AbbVie, Amgen, Eli-Lilly, Janssen, and Novartis.
Wayne Gulliver has served as advisor/consultant and received research grants from AbbVie…