The ocular surface and tear film and their dysfunction in dry eye disease

M Rolando, M Zierhut - Survey of ophthalmology, 2001 - Elsevier
The ocular surface, tear film, lacrimal glands, and eyelids act as a functional unit to preserve
the quality of the refractive surface of the eye and to resist injury and protect the eye against …

Adalimumab in the therapy of uveitis in childhood

…, D Doycheva, M Zierhut - British Journal of …, 2007 - bjo.bmj.com
Purpose: Chronic anterior uveitis in children often takes a serious course. Despite various
immunosuppressive drugs some children do not respond sufficiently and there is a high risk of …

Ocular adverse events after COVID-19 vaccination

…, I Testi, SL Ho, M Tien, WK Ngo, M Zierhut… - Ocular immunology …, 2021 - Taylor & Francis
Purpose The COVID-19 pandemic has galvanized the development of new vaccines at an
unprecedented pace. Since the widespread implementation of vaccination campaigns, …

Understanding uveitis: the impact of research on visual outcomes

…, E Miserocchi, PI Murray, U Pleyer, M Zierhut… - Progress in retinal and …, 2011 - Elsevier
The term uveitis encompasses a very diverse group of inflammatory ocular diseases that cause
a significant burden of legal and economic blindness. Indeed, the socioeconomic impact …

Secukinumab in the treatment of noninfectious uveitis: results of three randomized, controlled clinical trials

AD Dick, I Tugal-Tutkun, S Foster, M Zierhut, SHM Liew… - Ophthalmology, 2013 - Elsevier
PURPOSE: To determine the efficacy and safety of different doses of secukinumab, a fully
human monoclonal antibody for targeted interleukin-17A blockade, in patients with …

The use of interferon α in Behçet disease: review of the literature

I Kötter, I Günaydin, M Zierhut, N Stübiger - Seminars in arthritis and …, 2004 - Elsevier
OBJECTIVES: To evaluate the efficacy and safety of interferon (IFN) alpha for the treatment
of Behçet’s disease (BD) and discuss its possible mechanisms of action. METHODS: Reports …

Behçet's disease: ocular effects and treatment

…, GR Wallace, PI Murray, N Stübiger, M Zierhut - Progress in retinal and …, 2008 - Elsevier
Behçet's disease (BD) is a systemic immune-mediated vasculitis of unclear origin. Major
symptoms include oral aphthous ulcers, genital ulcerations, skin lesions, and ocular lesions. …

High frequency of MYD88 mutations in vitreoretinal B-cell lymphoma: a valuable tool to improve diagnostic yield of vitreous aspirates

…, C Deuter, D Süsskind, M Zierhut… - Blood, The Journal …, 2015 - ashpublications.org
Vitreoretinal diffuse large B-cell lymphoma is a rare disorder, occurring as primary ocular
disease or as secondary involvement by primary central nervous system lymphoma. It is …

Long‐term remission after cessation of interferon‐α treatment in patients with severe uveitis due to Behçet's disease

CME Deuter, M Zierhut, A Möhle… - Arthritis & …, 2010 - Wiley Online Library
Objective To retrospectively assess the development of visual acuity and the frequency and
duration of relapse‐free periods in patients who were treated with interferon‐α (IFNα) for …

[HTML][HTML] Safety and efficacy of adalimumab in patients with noninfectious uveitis in an ongoing open-label study: VISUAL III

…, A Schlaen, MEJ van Velthoven, AT Vitale, M Zierhut… - Ophthalmology, 2018 - Elsevier
Purpose To evaluate safety and efficacy of adalimumab in patients with noninfectious
intermediate, posterior, or panuveitis. Design Phase 3, open-label, multicenter clinical trial …