Survival analysis and causes of mortality in patients with lupus nephritis

DYH Yap, CSO Tang, MKM Ma… - Nephrology Dialysis …, 2012 - academic.oup.com
Background This study aimed to define the causes and associated risks of death compared
with the local general population in Chinese patients with lupus nephritis in the recent era. …

mTOR inhibition and kidney diseases

MKM Ma, S Yung, TM Chan - Transplantation, 2018 - journals.lww.com
Mammalian or mechanistic target of rapamycin (mTOR) is a serine-threonine kinase that plays
essential roles in cell growth, proliferation, metabolism, and survival. Increased activation …

Toward establishing core outcome domains for trials in kidney transplantation: report of the standardized outcomes in nephrology—kidney transplantation consensus …

…, L Rostaing, G Wong, MA Josephson… - …, 2017 - journals.lww.com
Background Treatment decisions in kidney transplantation requires patients and clinicians
to weigh the benefits and harms of a broad range of medical and surgical interventions, but …

Association between delayed graft function and graft loss in donation after cardiac death kidney transplants—a paired kidney registry analysis

…, SP McDonald, GR Russ, JR Chapman, MKM Ma… - …, 2017 - journals.lww.com
Background Delayed graft function (DGF) is an established complication after donation after
cardiac death (DCD) kidney transplants, but the impact of DGF on graft outcomes is …

Acute rejection, T-cell–depleting antibodies, and cancer after transplantation

WH Lim, RM Turner, JR Chapman, MKM Ma… - …, 2014 - journals.lww.com
Background Systemic inflammatory response has been shown to play a vital role in
carcinogenesis and tumor progression. Acute rejection is a systemic inflammatory state and may …

Longterm data on sirolimus treatment in patients with lupus nephritis

…, C Tang, GCW Chan, LPY Kwan, MKM Ma… - The Journal of …, 2018 - jrheum.org
Objective. To expand the limited longterm data on sirolimus treatment in patients with lupus
nephritis (LN). Our pilot short-term data suggested efficacy of sirolimus treatment in these …

Long-term data on corticosteroids and mycophenolate mofetil treatment in lupus nephritis

DYH Yap, MKM Ma, MMY Mok, CSO Tang… - …, 2013 - academic.oup.com
Objective. We investigated the long-term outcome of patients with proliferative LN treated
with CSs and MMF. Methods. This was a single-centre retrospective study on patients with …

Mortality among younger and older recipients of kidney transplants from expanded criteria donors compared with standard criteria donors

MKM Ma, WH Lim, JC Craig, GR Russ… - Clinical Journal of the …, 2016 - journals.lww.com
Results In total, 3822 patients were transplanted between 1997 and 2009. Over a follow-up
period of 21,249 person-years (a median duration of 5.3 years [interquartile range, 2.22–8.6 …

Longterm data on disease flares in patients with proliferative lupus nephritis in recent years

DYH Yap, C Tang, MKM Ma, MMY Mok… - The Journal of …, 2017 - jrheum.org
Objective. To examine the disease flare rate in lupus nephritis (LN), focusing on renal flares,
and the factors associated with relapse risk in recent years. Methods. We analyzed data on …

Effect of mycophenolate and rapamycin on renal fibrosis in lupus nephritis

…, KF Cheung, MKM Chau, DYH Yap, MKM Ma… - Clinical …, 2019 - portlandpress.com
Lupus nephritis (LN) leads to chronic kidney disease (CKD) through progressive fibrosis.
Mycophenolate inhibits inosine monophosphate dehydrogenase and is a standard treatment …