Selective expression of folate receptor β and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis

…, N Sunahara, T Nakamura, M Tsukano… - … : Official Journal of …, 1999 - Wiley Online Library
Objective To investigate the expression of folate receptors (FR) and reduced folate carrier (RFC)
and determine their relevance to methotrexate (MTX) transport in synovial mononuclear …

Polyarteritis nodosa limited to calf muscles: a case report and review of the literature

T Nakamura, K Tomoda, Y Yamamura, M Tsukano… - Clinical …, 2003 - Springer
We describe an unusual case of a 38-year-old woman with a localised form of polyarteritis
nodosa (PAN) manifested by acute onset of severe calf pain. Magnetic resonance imaging of …

Beneficial effect of galectin 9 on rheumatoid arthritis by induction of apoptosis of synovial fibroblasts

…, SY Dai, S Katoh, N Nishi, M Tsukano… - … : Official Journal of …, 2007 - Wiley Online Library
Objective To compare the expression of galectin 9 (Gal‐9) in synovial tissue (ST) from
rheumatoid arthritis (RA) patients and osteoarthritis (OA) patients and to evaluate the effects of Gal…

[HTML][HTML] Synoviocyte-derived angiopoietin-like protein 2 contributes to synovial chronic inflammation in rheumatoid arthritis

T Okada, H Tsukano, M Endo, M Tabata… - The American journal of …, 2010 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by symmetrical
polyarticular synovitis of the diarthrodial joints. Several proinflammatory cytokines derived from …

Continuation of methotrexate resulted in better clinical and radiographic outcomes than discontinuation upon starting etanercept in patients with rheumatoid arthritis …

…, S Nagaoka, T Hidaka, T Atsumi, M Tsukano… - The Journal of …, 2011 - jrheum.org
Objective. The aim of the Efficacy and Safety of Etanercept on Active Rheumatoid Arthritis
Despite Methotrexate Therapy in Japan (JESMR) study is to compare the efficacy of …

Efficacy and safety of olokizumab in Asian patients with moderate-to-severe rheumatoid arthritis, previously exposed to anti-TNF therapy: results from a randomized …

…, W Park, K Shiozawa, M Tsukano… - Modern …, 2016 - academic.oup.com
Objectives: This phase II, dose-ranging, double-blind, placebo-controlled, randomized study
(NCT01463059) evaluated efficacy and safety of olokizumab (OKZ), a humanized anti-…

Etanercept (ETN) with methotrexate (MTX) is better than ETN monotherapy in patients with active rheumatoid arthritis despite MTX therapy: a randomized trial

…, T Hidaka, T Atsumi, M Tsukano… - Modern …, 2010 - academic.oup.com
The superiority of the combination therapy of methotrexate (MTX) and anti-tumor necrosis
factor (TNF) biological agents over anti-TNF monotherapy in MTX-naïve patients with …

Mycobacterium kansasii arthritis of the foot in a patient with systemic lupus erythematosus

…, K Tomoda, M SAKAGUCHI, M TSUKANO - Internal …, 2001 - jstage.jst.go.jp
Mycobacteriumkansasii, an atypical Mycobacterium, may cause serious illness in humans.
Wedescribe a M. kansasii infection of the foot joint, which was diagnosed in a 46-year-old …

Etanercept can induce resolution of renal deterioration in patients with amyloid A amyloidosis secondary to rheumatoid arthritis

T Nakamura, S Higashi, K Tomoda, M Tsukano… - Clinical …, 2010 - Springer
The benefit of biological therapies in rheumatoid arthritis (RA) treatment is well known, but
their role in amyloid A (AA) amyloidosis secondary to RA is unclear. The aim of this study was …

Effectiveness of etanercept vs cyclophosphamide as treatment for patients with amyloid A amyloidosis secondary to rheumatoid arthritis

T Nakamura, S Higashi, K Tomoda, M Tsukano… - …, 2012 - academic.oup.com
Objectives. To compare the effectiveness of an alkylating agent with that of a biologic agent
in the treatment of patients with amyloid A (AA) amyloidosis secondary to RA and to assess …