Objective The 1980 American College of Rheumatology (ACR) classification criteria for
systemic sclerosis (SSc) lack sensitivity for early SSc and limited cutaneous SSc. The present …

Objective. To provide a single source for the best available estimates of the US prevalence of
and number of individuals affected by arthritis overall, rheumatoid arthritis, juvenile arthritis, …

Objective To estimate the prevalence, incidence, survival, and disease characteristics of
systemic sclerosis (SSc) in the Detroit tricounty area. Methods A census of SSc cases for the …

Background Interstitial lung disease (ILD) is a common manifestation of systemic sclerosis
and a leading cause of systemic sclerosis–related death. Nintedanib, a tyrosine kinase …

Objective. The 1980 American College of Rheuma-tology (ACR) classification criteria for
systemic sclerosis (SSc) lack sensitivity for early SSc and limited cutaneous SSc. The present …

Objectives Ischaemic digital ulcers (DUs) are common in patients with systemic sclerosis (SSc)
and are a cause of disease-related morbidity. In an earlier trial, treatment with bosentan, …

Background Despite current therapies, diffuse cutaneous systemic sclerosis (scleroderma)
often has a devastating outcome. We compared myeloablative CD34+ selected autologous …

Objective To evaluate CAT‐192, a recombinant human antibody that neutralizes transforming
growth factor β1 (TGFβ1), in the treatment of early‐stage diffuse cutaneous systemic …

Objective To document disease activity and functional status in patients with scleroderma (systemic
sclerosis [SSc]) and Raynaud's phenomenon (RP) and to determine the sensitivity to …

Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and
internal organs that leads to profound disability and premature death. To identify new SSc …