Autoantibodies in the serum from a patient with connective tissue disease have been used
to define a high molecule weight acidic nuclear protein antigen. The antigen tentatively …

The clinical significance of antibodies to the Jo‐1 antigen in connective tissue diseases was
studied. Clinical diagnoses of 11 patients who had anti‐Jo‐1 antibody were: polymyositis 8, …

Autoantibodies to five of the aminoacyl-transfer RNA (tRNA) synthetases have been described,
and each is associated with a syndrome of inflammatory myopathy with interstitial lung …

Four patients, treated for hematologic disorders with bone-marrow transplants from HLA-identical
siblings, spontaneously complained of dry eyes 8 to 12 months after transplantation. …

Objective. To elucidate the profile and clinical significance of autoantibodies to small nuclear
and small cytoplasmic ribonucleoproteins in Japanese patients with polymyositis and …

OBJECTIVE To evaluate methotrexate treatment in patients with active adult onset Still’s
disease (AOSD). METHODS Methotrexate was initially given as a single weekly oral dose of 5 …

Anti-Ku (p70/p80) autoantibodies in patients with scleroderma-polymyositis overlap syndrome
recognize a 70-kDa/80-kDa protein heterodimer which binds to terminal regions of double-…

Objective To determine the clinical features of methotrexate (MTX) pneumonitis in patients
treated for rheumatoid arthritis (RA). Methods The medical records of 284 patients with RA …

Objective. Takayasu arteritis (TAK) is a rare autoimmune arteritis that affects large arteries.
Although the association between TAK and HLA-B*52:01 is established, the other …

Objective To evaluate the specificity of anti‐DEK antibodies for juvenile rheumatoid arthritis (JRA).
Methods Anti‐DEK autoantibodies were measured by enzyme‐linked immunosorbent …