[HTML][HTML] Baseline predictors of response and discontinuation of tumor necrosis factor-alpha blocking therapy in ankylosing spondylitis: a prospective longitudinal …

…, E van der Veer, H Groen, MK Leijsma… - Arthritis research & …, 2011 - Springer
Introduction Identifying ankylosing spondylitis (AS) patients who are likely to benefit from
tumor necrosis factor-alpha (TNF-α) blocking therapy is important, especially in view of the …

[HTML][HTML] The relation between bone mineral density, bone turnover markers, and vitamin D status in ankylosing spondylitis patients with active disease: a cross …

…, GAW Bruyn, PM Houtman, MK Leijsma… - Osteoporosis …, 2011 - Springer
Osteoporosis is a well recognized complication of ankylosing spondylitis (AS). This study
indicates that increased bone turnover, inflammation, and low vitamin D levels are important in …

Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis

…, T Saxne, A Krabben, MK Leijsma… - Annals of the …, 2013 - ard.bmj.com
Background Progression of joint destruction in rheumatoid arthritis (RA) is partly heritable;
knowledge of genetic factors may increase our understanding of the mechanisms underlying …

Sjögren's syndrome and localized nodular cutaneous amyloidosis: coincidence or a distinct clinical entity?

…, O Ciocca, V Perfetti, MK Leijsma… - … : Official Journal of …, 2008 - Wiley Online Library
Objective. To report 8 patients with Sjögren’s syndrome (SS) and localized nodular cutaneous
amyloidosis and to examine serologic and immunohistologic findings that may link the 2 …

[HTML][HTML] The effect of three years of TNF alpha blocking therapy on markers of bone turnover and their predictive value for treatment discontinuation in patients with …

…, A Spoorenberg, PM Houtman, MK Leijsma… - Arthritis research & …, 2012 - Springer
Introduction The aim of this study was to investigate the effect of three years of tumor necrosis
factor-alpha (TNF-α) blocking therapy on bone turnover as well as to analyze the predictive …

Serum MMP-3 level as a biomarker for monitoring and predicting response to etanercept treatment in ankylosing spondylitis

…, TIMLTA JANSEN, MK LEIJSMA… - The Journal of …, 2011 - jrheum.org
Objective. To investigate whether level of serum matrix metalloproteinase-3 (MMP-3) can serve
as a biomarker for monitoring and predicting response to etanercept treatment in patients …

[HTML][HTML] Higher bone turnover is related to spinal radiographic damage and low bone mineral density in ankylosing spondylitis patients with active disease: a cross …

S Arends, A Spoorenberg, M Efde, R Bos, MK Leijsma… - PLoS …, 2014 - journals.plos.org
Introduction Ankylosing spondylitis (AS) is characterized by excessive bone formation and
bone loss. Our aim was to investigate the association of bone turnover markers (BTM) with …

Laryngeal presentation of systemic apolipoprotein A‐I–derived amyloidosis

…, J Gilbertson, MD Posthumus, MK Leijsma… - The …, 2009 - Wiley Online Library
Objective: To study the clinical and pathological characteristics of two patients with laryngeal
apolipoprotein A‐I (apoA‐I)‐derived (AApoAI) amyloidosis with the apolipoprotein A‐I …

[HTML][HTML] A genetic variant in osteoprotegerin is associated with progression of joint destruction in rheumatoid arthritis

…, T Saxne, E Lindqvist, MK Leijsma… - Arthritis research & …, 2014 - Springer
Introduction Progression of joint destruction in rheumatoid arthritis (RA) is partly heritably;
45 to 58% of the variance in joint destruction is estimated to be explained by genetic factors. …

[HTML][HTML] Pulmonary medium vessel vasculitis in an 11 year old boy: Hughes Stovin syndrome as a variant of polyarteritis nodosa?

…, MTR Roofthooft, H Bootsma, MK Leijsma… - Pediatric …, 2011 - Springer
We present the case of an 11-year-old boy presenting with haemoptysis, dyspnoea and
weight loss as a manifestation of isolated pulmonary vasculitis, leading to pulmonary …