[HTML][HTML] Immunological changes in human skeletal muscle and blood after eccentric exercise and multiple biopsies
C Malm, P Nyberg, M Engström, B Sjödin… - The Journal of …, 2000 - ncbi.nlm.nih.gov
A role of the immune system in muscular adaptation to physical exercise has been
suggested but data from controlled human studies are scarce. The present study investigated …
suggested but data from controlled human studies are scarce. The present study investigated …
Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss
…, M Sun, N Vivar, AJ Ytterberg, M Engström… - Annals of the …, 2016 - ard.bmj.com
Objectives Rheumatoid arthritis (RA)-specific anti-citrullinated protein/peptide antibodies (ACPAs)
appear before disease onset and are associated with bone destruction. We aimed to …
appear before disease onset and are associated with bone destruction. We aimed to …
Structural changes and antibody enrichment in the lungs are early features of anti–citrullinated protein antibody–positive rheumatoid arthritis
…, AH Hensvold, A Harju, M Engström… - Arthritis & …, 2014 - Wiley Online Library
Objective It has been suggested that immunologic events in the lungs may be involved in
triggering immunity, in particular production of anti–citrullinated protein antibodies (ACPAs) …
triggering immunity, in particular production of anti–citrullinated protein antibodies (ACPAs) …
Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition
…, V Joshua, M Engström… - Journal of Experimental …, 2013 - rupress.org
Antibodies targeting citrullinated proteins (ACPAs [anticitrullinated protein antibodies]) are
commonly found in patients with rheumatoid arthritis (RA), strongly associate with distinct HLA-…
commonly found in patients with rheumatoid arthritis (RA), strongly associate with distinct HLA-…
Evidence that anti–tumor necrosis factor therapy with both etanercept and infliximab induces apoptosis in macrophages, but not lymphocytes, in rheumatoid arthritis …
…, C Trollmo, E af Klint, M Engstrom… - … : Official Journal of …, 2005 - Wiley Online Library
Objective Treatment of rheumatoid arthritis (RA) with tumor necrosis factor (TNF) antagonists
is highly effective, but their mechanisms of action are not completely clear. Since anti‐TNF …
is highly effective, but their mechanisms of action are not completely clear. Since anti‐TNF …
Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis
…, H Olsen, V Joshua, M Engström… - Annals of the …, 2016 - ard.bmj.com
Objectives Events in the lungs might contribute to generation of anticitrullinated protein
antibodies (ACPA) in rheumatoid arthritis (RA). We investigated if signs of immune activation are …
antibodies (ACPA) in rheumatoid arthritis (RA). We investigated if signs of immune activation are …
Systemic anti–tumor necrosis factor α therapy in rheumatoid arthritis down‐regulates synovial tumor necrosis factor α synthesis
AK Ulfgren, U Andersson, M Engström… - … : Official Journal of …, 2000 - Wiley Online Library
Objective To investigate the hypothesis that tumor necrosis factor α (TNFα) blockade in
rheumatoid arthritis (RA) diminishes synovial synthesis of TNFα, interleukin‐1α (IL‐1α), and IL‐1β…
rheumatoid arthritis (RA) diminishes synovial synthesis of TNFα, interleukin‐1α (IL‐1α), and IL‐1β…
[HTML][HTML] Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of …
M Engström, K Eriksson, L Lee, M Hermansson… - Journal of translational …, 2018 - Springer
Background A relationship between rheumatoid arthritis (RA) and periodontitis has been
suggested from findings that individuals with RA are prone to have advanced periodontitis and …
suggested from findings that individuals with RA are prone to have advanced periodontitis and …
Intraarticular glucocorticoid treatment reduces inflammation in synovial cell infiltrations more efficiently than in synovial blood vessels
E Klint, C Grundtman, M Engström… - Arthritis & …, 2005 - Wiley Online Library
Objective To investigate whether intraarticular (IA) glucocorticoid (GC) therapy diminishes
synovial cell infiltration, vascularity, expression of proinflammatory cytokines, and adhesion …
synovial cell infiltration, vascularity, expression of proinflammatory cytokines, and adhesion …
Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis
…, U Hardt, A Krishnamurthy, J Steen, M Engström… - Journal of …, 2017 - Elsevier
Oxidation-associated malondialdehyde (MDA) modification of proteins can generate immunogenic
neo-epitopes that are recognized by autoantibodies. In health, IgM antibodies to MDA…
neo-epitopes that are recognized by autoantibodies. In health, IgM antibodies to MDA…