… We also examined the uptake of 3H-MTX in RA SMC in studies using 0.2 M 3H-MTX in the
presence or absence of folic acid. This has been reported to be the therapeutic concentration …

We describe an unusual case of a 38-year-old woman with a localised form of polyarteritis
nodosa (PAN) manifested by acute onset of severe calf pain. Magnetic resonance imaging of …

Objective To compare the expression of galectin 9 (Gal‐9) in synovial tissue (ST) from
rheumatoid arthritis (RA) patients and osteoarthritis (OA) patients and to evaluate the effects of Gal…

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by symmetrical
polyarticular synovitis of the diarthrodial joints. Several proinflammatory cytokines derived from …

… the erosion score was negative in the E+M group, which was significantly better than the E …
the E+M group than in the E group. ACR20, 50, and 70 response rates at Week 52 in the E+M …

Objective. To clarify the clinical significance of the SAA1.3 allele in the development and
outcome of AA amyloidosis in Japanese patients with rheumatoid arthritis (RA). Methods. One …

… higher in the E + M group (52%) than … M group (64 and 38%, respectively) than in the E
group (48 and 26%, respectively), the ACR20 response rate was significantly greater in the E + M …

Objectives: This phase II, dose-ranging, double-blind, placebo-controlled, randomized study
(NCT01463059) evaluated efficacy and safety of olokizumab (OKZ), a humanized anti-…

Mycobacteriumkansasii, an atypical Mycobacterium, may cause serious illness in humans.
Wedescribe a M. kansasii infection of the foot joint, which was diagnosed in a 46-year-old …

The benefit of biological therapies in rheumatoid arthritis (RA) treatment is well known, but
their role in amyloid A (AA) amyloidosis secondary to RA is unclear. The aim of this study was …