We recently discovered the Kaposi's sarcoma-associated herpes virus (KSHV/HHV-8) in an
uncommon and unusual subset of AIDS-related lymphomas that grow mainly in the body …

Context—Timely and accurate diagnosis of hematologic malignancies is crucial to appropriate
clinical management. Acute leukemias are a diverse group of malignancies with a range …

Five patients with advanced AIDS developed a unique type of high grade primary body
cavity-based non-Hodgkin’s lymphoma (NHL). The lymphomas were exclusively in serous …

Context.— The process for identifying patients with monoclonal gammopathies is complex.
Initial detection of a monoclonal immunoglobulin protein (M protein) in the serum or urine …

Systemic anaphylaxis is an acute allergic emergency resulting from generalized mast cell
degranulation. In the United States, it is estimated that anaphylaxis accounts for about 500 …

Context Flow cytometry is often applied to minimal residual disease (MRD) testing in
hematolymphoid neoplasia. Because flow-based MRD tests are developed in the laboratory, testing …

We reviewed our institutional experience with de novo CD5+, large B-cell lymphomas to
determine whether they represent a distinct entity and are related to CD5+ small B-cell disorders…

Context.—Syphilis serology screening in laboratory practice is evolving. Traditionally, the
syphilis screening algorithm begins with a nontreponemal immunoassay, which is manually …

Objective This study was conducted to determine the spectrum of laboratory practices in
antinuclear antibody (ANA) test target, performance, and result reporting. Methods A …

Objective: To assess the false-positive and false-negative rates of a 4th-generation human
immunodeficiency virus (HIV) assay, the Abbott ARCHITECT, vs 2 HIV 3rd-generation assays, …