[HTML][HTML] Immunosenescence and infectious diseases

…, MF Loreto, MP Corsi, M Modesti, M De Martinis - Microbes and …, 2001 - Elsevier
Infectious diseases are major causes, with malignancies, of morbidity and mortality in the
elderly. Increased susceptibility to infections may result from underlying dysfunction of an aged …

A common repertoire of autoantibodies is shared by cancer and autoimmune disease patients: Inflammation in their induction and impact on tumor growth

R Bei, L Masuelli, C Palumbo, M Modesti, A Modesti - Cancer letters, 2009 - Elsevier
The repertoire of autoantibodies found in cancer patients partly overlaps with that typical of
patients with autoimmune diseases. Beside the biochemical and immunological properties of …

[HTML][HTML] DNA repair: spot (light) s on chromatin

M Modesti, R Kanaar - Current Biology, 2001 - cell.com
Chromatin modifications regulate many nuclear processes. Recent studies on the
phosphorylation of a histone 2A variant have revealed that this chromatin modification is a …

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

…, HT Brüggenwirth, M Modesti… - Proceedings of the …, 2006 - National Acad Sciences
DNA double-strand break (DSB) repair by nonhomologous end joining (NHEJ) requires the
assembly of several proteins on DNA ends. Although biochemical studies have elucidated …

Expandable graphite as an intumescent flame retardant in polyisocyanurate–polyurethane foams

M Modesti, A Lorenzetti, F Simioni, G Camino - Polymer Degradation and …, 2002 - Elsevier
… The cone calorimeter exposes a small square horizontal test specimen (100×100×25 mm)
to a preset heat flux (in our case 50 kW/m 2 ), in the presence of an air flow (24 l/s), ignited by …

Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging

…, M Modesti, M Falkenberg… - Proceedings of the …, 2009 - National Acad Sciences
Single-molecule manipulation studies have revealed that double-stranded DNA undergoes
a structural transition when subjected to tension. At forces that depend on the attachment …

The structure‐specific endonuclease Mus81–Eme1 promotes conversion of interstrand DNA crosslinks into double‐strands breaks

K Hanada, M Budzowska, M Modesti, A Maas… - The EMBO …, 2006 - embopress.org
Repair of interstrand crosslinks (ICLs) requires multiple‐strand incisions to separate the two
covalently attached strands of DNA. It is unclear how these incisions are generated. DNA …

[PDF][PDF] Rab6 regulates transport and targeting of exocytotic carriers

…, PS Wulf, J Demmers, T Ohtsuka, M Modesti… - Developmental cell, 2007 - cell.com
Constitutive exocytosis delivers newly synthesized proteins, lipids, and other molecules from
the Golgi apparatus to the cell surface. This process is mediated by vesicles, which bud off …

Primary Sjögren's syndrome as a multi-organ disease: impact of the serological profile on the clinical presentation of the disease in a large cohort of Italian patients

…, A Alunno, A Gattamelata, M Maset, M Modesti… - …, 2014 - academic.oup.com
Objective. The aims of this study were to describe the clinical presentation of primary SS (pSS)
in a large cohort of patients by assessing the prevalence of the patient subgroups at high …

Effect of processing conditions on morphology and mechanical properties of compatibilized polypropylene nanocomposites

M Modesti, A Lorenzetti, D Bon, S Besco - Polymer, 2005 - Elsevier
This work focuses on the influence of processing conditions on the nanocomposites
structure, ie intercalated or exfoliated, and on the enhancement of mechanical properties of …