OBJECTIVE: Although osteoarthritis (OA) is considered a non-inflammatory condition, it is
widely accepted that synovial inflammation is a feature of OA. However, the role of immune …

Objectives: To develop evidence-based recommendations for the diagnosis of hand
osteoarthritis (OA). Methods: The multidisciplinary guideline development group, representing 15 …

Over the past year many studies and clinical trials have been published in the osteoarthritis (OA)
field. This review is based on systematic literature review covering the period May 1 st , …

Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide
association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and …

Disease incidences increase with age, but the molecular characteristics of ageing that lead
to increased disease susceptibility remain inadequately understood. Here we perform a …

Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are
highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other …

… Preferentially, the cut-off of BMI is 25 kg/m2, as the World Health Organization definition
for overweight could be used.43 However, this was the case in only a minority of studies. …

Purpose: To prospectively evaluate the association between clinical features and structural
abnormalities found at magnetic resonance (MR) imaging in patients with osteoarthritis (OA) …

Since publication of the European League Against Rheumatism (EULAR) recommendations
for management of hand osteoarthritis (OA) in 2007 new evidence has emerged. The aim …

Objective To systematically evaluate the association between MRI findings (cartilage defects,
bone marrow lesions (BML), osteophytes, meniscal lesion, effusion/synovitis, ligamentous …