Priming of the neutrophil respiratory burst: role in host defense and inflammation
J El‐Benna, M Hurtado‐Nedelec… - Immunological …, 2016 - Wiley Online Library
… M). The priming agents alone induce either a very weak or no response, but … M fMLF), but
activate ROS production at higher concentrations 33-38. We have always used fMLF (>10 −7 M…
activate ROS production at higher concentrations 33-38. We have always used fMLF (>10 −7 M…
[HTML][HTML] Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity
…, M Hurtado-Nedelec, S Luce, K Bailly, M Andrieu… - Nature …, 2021 - nature.com
Immune system dysfunction is paramount in coronavirus disease 2019 (COVID-19) severity
and fatality rate. Mucosal-associated invariant T (MAIT) cells are innate-like T cells involved …
and fatality rate. Mucosal-associated invariant T (MAIT) cells are innate-like T cells involved …
NADPH oxidase activation in neutrophils: Role of the phosphorylation of its subunits
…, L Rolas, H Raad, M Hurtado‐Nedelec… - European journal of …, 2018 - Wiley Online Library
Neutrophils are key cells of innate immunity and during inflammation. Upon activation, they
produce large amounts of superoxide anion (O 2 −. ) and ensuing reactive oxygen species ( …
produce large amounts of superoxide anion (O 2 −. ) and ensuing reactive oxygen species ( …
Characterization of the immune response in the synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome
M Hurtado-Nedelec, S Chollet-Martin… - …, 2008 - academic.oup.com
Objective. The aetiology of SAPHO (synovitis, acne, palmoplantar pustulosis, hyperostosis,
osteitis) syndrome seems to involve genetic, infectious and immunological components. We …
osteitis) syndrome seems to involve genetic, infectious and immunological components. We …
An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis
…, C Ganneau, M Hurtado-Nedelec… - Science translational …, 2019 - science.org
Anaphylaxis is a systemic acute hypersensitivity reaction that is considered to depend on
allergen-specific immunoglobulin E (IgE) antibodies and histamine release by mast cells and …
allergen-specific immunoglobulin E (IgE) antibodies and histamine release by mast cells and …
Leukocyte activation: the link between inflammation and coagulation during heatstroke. A study of patients during the 2003 heat wave in Paris
MG Huisse, S Pease, M Hurtado-Nedelec… - Critical care …, 2008 - journals.lww.com
Objective: The mechanisms linking severe inflammation and coagulation during heatstroke
are poorly understood. Here, we examined the roles of the tissue factor pathway, leukocyte …
are poorly understood. Here, we examined the roles of the tissue factor pathway, leukocyte …
Zymosan induces NADPH oxidase activation in human neutrophils by inducing the phosphorylation of p47phox and the activation of Rac2: involvement of protein …
…, M Chiandotto, M Hurtado-Nedelec… - Biochemical …, 2013 - Elsevier
Reactive oxygen species (ROS) production by the neutrophil NADPH oxidase plays a key
role in host defense against pathogens, such as bacteria and fungi. Zymosan a cell-wall …
role in host defense against pathogens, such as bacteria and fungi. Zymosan a cell-wall …
[HTML][HTML] Luminol-amplified chemiluminescence detects mainly superoxide anion produced by human neutrophils
…, F Moulti-Mati, M Hurtado-Nedelec… - American journal of …, 2017 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) are produced by numerous biological systems and by several
phagocytes such as neutrophils and macrophages. ROS include mostly superoxide anion…
phagocytes such as neutrophils and macrophages. ROS include mostly superoxide anion…
Erythropoietin stimulates spleen BMP4-dependent stress erythropoiesis and partially corrects anemia in a mouse model of generalized inflammation
…, S Lyoumi, M Hurtado-Nedelec… - Blood, The Journal …, 2010 - ashpublications.org
Mouse bone marrow erythropoiesis is homeostatic, whereas after acute anemia, bone
morphogenetic protein 4 (BMP4)–dependent stress erythropoiesis develops in the spleen. The …
morphogenetic protein 4 (BMP4)–dependent stress erythropoiesis develops in the spleen. The …
Pulmonary manifestations in adult patients with chronic granulomatous disease
…, M Hurtado-Nedelec… - European …, 2015 - Eur Respiratory Soc
Chronic granulomatous disease (CGD) is a primary immunodeficiency caused by failure of
superoxide production in phagocytic cells. The disease is characterised by recurrent …
superoxide production in phagocytic cells. The disease is characterised by recurrent …