Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project
…, M Bortlík, BJA Crusius, M Vecchi, M Artieda… - Gut, 2013 - gut.bmj.com
Objective Through genome-wide association scans and meta-analyses thereof, over 70
genetic loci (Crohn's disease (CD) single nucleotide polymorphisms (SNPs)) are significantly …
genetic loci (Crohn's disease (CD) single nucleotide polymorphisms (SNPs)) are significantly …
Can we identify a power-oriented polygenic profile?
…, D Arteta, A Buxens, M Artieda… - Journal of Applied …, 2010 - journals.physiology.org
… race; the performance of the world best competitors in 100-m sprint or the long jump is
negatively correlated with performance in the 1,500-m race (36). There seems to exist a “trade-off,…
negatively correlated with performance in the 1,500-m race (36). There seems to exist a “trade-off,…
Serum chitotriosidase activity is increased in subjects with atherosclerosis disease
M Artieda, A Cenarro, A Gañán, I Jericó… - … , and vascular biology, 2003 - Am Heart Assoc
Objective— This study was undertaken to analyze the relation between serum activity of
chitotriosidase enzyme, a protein synthesized exclusively by activated macrophages, and …
chitotriosidase enzyme, a protein synthesized exclusively by activated macrophages, and …
A common variant in the ABCA1 gene is associated with a lower risk for premature coronary heart disease in familial hypercholesterolaemia
A Cenarro, M Artieda, S Castillo, P Mozas… - Journal of medical …, 2003 - jmg.bmj.com
Familial hypercholesterolaemia (FH) is a common autosomal codominant hereditary
disease caused by defects in the LDL receptor (LDLR) gene, and one of the most common …
disease caused by defects in the LDL receptor (LDLR) gene, and one of the most common …
Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease
…, E Vazeille, M Artieda, HW Verspaget, M Szczypiorska… - Gut, 2014 - gut.bmj.com
Objective Altered microbiota composition, changes in immune responses and impaired
intestinal barrier functions are observed in IBD. Most of these features are controlled by …
intestinal barrier functions are observed in IBD. Most of these features are controlled by …
The −786 T/C polymorphism of the NOS3 gene is associated with elite performance in power sports
F Gómez-Gallego, JR Ruiz, A Buxens, M Artieda… - European Journal of …, 2009 - Springer
The NOS3 gene is a candidate to explain individual variations in health and exercise
related phenotypes. We compared genotypic and allelic frequencies of the NOS3 −786 T/C …
related phenotypes. We compared genotypic and allelic frequencies of the NOS3 −786 T/C …
Reliable low-density DNA array based on allele-specific probes for detection of 118 mutations causing familial hypercholesterolemia
…, E Jiménez, M Lopez, MT Tejedor, M Artieda… - Clinical …, 2005 - academic.oup.com
Background: Patients with familial hypercholesterolemia (FH) have a high risk of premature
cardiovascular disease (PCVD). Mutations in the LDL receptor (LDLR) gene and the …
cardiovascular disease (PCVD). Mutations in the LDL receptor (LDLR) gene and the …
The− 174 G/C polymorphism of the IL6 gene is associated with elite power performance
… The VO 2max of controls was estimated from the time to complete 2000 m tests. The tests
were performed inside a 400-m outdoor track under similar environmental conditions (…
were performed inside a 400-m outdoor track under similar environmental conditions (…
[HTML][HTML] Tendon xanthomas in familial hypercholesterolemia are associated with a differential inflammatory response of macrophages to oxidized LDL
M Artieda, A Cenarro, C Junquera, P Lasierra… - FEBS letters, 2005 - Elsevier
Tendon xanthomas (TX) are pathognomonic lipid deposits commonly found in familial
hypercholesterolemia (FH) patients. The aim of this study was to determine whether macrophages …
hypercholesterolemia (FH) patients. The aim of this study was to determine whether macrophages …
The C677T polymorphism in the MTHFR gene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population
…, MC Ramirez, D Tejedor, M Artieda… - Scandinavian journal …, 2012 - Taylor & Francis
Objective: Methotrexate (MTX) is the first-choice drug for the treatment of rheumatoid arthritis
(RA) patients. However, 30% of RA patients discontinue therapy within 1 year, usually …
(RA) patients. However, 30% of RA patients discontinue therapy within 1 year, usually …