Optical coherence tomography: an emerging technology for biomedical imaging and optical biopsy

JG Fujimoto, C Pitris, SA Boppart, ME Brezinski - Neoplasia, 2000 - Elsevier
Optical coherence tomography (OCT) is an emerging technology for performing high-resolution
cross-sectional imaging. OCT is analogous to ultrasound imaging, except that it uses …

In vivo endoscopic optical biopsy with optical coherence tomography

GJ Tearney, ME Brezinski, BE Bouma, SA Boppart… - Science, 1997 - science.org
Current medical imaging technologies allow visualization of tissue anatomy in the human
body at resolutions ranging from 100 micrometers to 1 millimeter. These technologies are …

[PDF][PDF] Optical biopsy and imaging using optical coherence tomography

JG Fujimoto, ME Brezinski, GJ Tearney, SA Boppart… - 1995 - researchgate.net
The technology of OCT Optical coherence tomography performs micrometre-scale, cross-sectional
imaging of tissue structure in biological systems by directing a focused beam of light …

Determination of the refractive index of highly scattering human tissue by optical coherence tomography

GJ Tearney, ME Brezinski, JF Southern, BE Bouma… - Optics letters, 1995 - opg.optica.org
We describe two new techniques, based on optical coherence tomography (OCT), for
determining the refractive index of highly scattering human tissue. We obtained refractive indices …

Optical coherence tomography for optical biopsy: properties and demonstration of vascular pathology

ME Brezinski, GJ Tearney, BE Bouma, JA Izatt… - Circulation, 1996 - Am Heart Assoc
Background Optical coherence tomography (OCT) is a recently developed medical
diagnostic technology that uses back-reflected infrared light to perform in situ micron scale …

[BOOK][B] Optical coherence tomography: principles and applications

ME Brezinski - 2006 - books.google.com
… Harman, and ME Brezinski, 2005. Variables affecting polarization sensitive optical
coherence tomography imaging examined through the modeling of birefringent phantoms. J. …

Scanning single-mode fiber optic catheter–endoscope for optical coherence tomography

GJ Tearney, SA Boppart, BE Bouma, ME Brezinski… - Optics letters, 1996 - opg.optica.org
We describe a new optical coherence tomography catheter–endoscope for micrometer-scale,
cross-sectional imaging in internal organ systems. The catheter–endoscope uses single-…

Assessing atherosclerotic plaque morphology: comparison of optical coherence tomography and high frequency intravascular ultrasound.

ME Brezinski, GJ Tearney, NJ Weissman, SA Boppart… - Heart, 1997 - heart.bmj.com
BACKGROUND: OCT can image plaque microstructure at a level of resolution not previously
demonstrated with other imaging techniques because it uses infrared light rather than …

High-resolution optical coherence tomographic imaging using a mode-locked Ti:Al2O3 laser source

…, GJ Tearney, SA Boppart, MR Hee, ME Brezinski… - Optics letters, 1995 - opg.optica.org
A Kerr-lens mode-locked Ti:Al_2O_3 oscillator, optimized for minimal coherence length, is
demonstrated as a high-power source for high-resolution optical coherence tomographic …

New Technology for High‐Speed and High‐Resolution Optical Coherence Tomographya

…, C Pitris, JF Southern, ME Brezinski - Annals of the New …, 1998 - Wiley Online Library
Optical coherence tomography (OCT) is an attractive technique for optical biopsy because it
can permit the imaging of tissue microstructure in situ yielding micron-scale image …