… Fransen 2007 reported one withdrawal in the Tai Chi allocation group that was due to
increased low back pain. The largest numbers of adverse events were reported by Bennell 2010 (…

Objective To determine whether land-based therapeutic exercise is beneficial for people
with knee osteoarthritis (OA) in terms of reduced joint pain or improved physical function and …

… mitochondrial redox balance is disturbed in cells lacking catalase or functional peroxisomes,
and upon the generation of excess ROS inside peroxisomes [69; Apanasets and Fransen, …

Background Non-fatal health outcomes from diseases and injuries are a crucial consideration
in the promotion and monitoring of individual and population health. The Global Burden of …

Background Measuring disease and injury burden in populations requires a composite metric
that captures both premature mortality and the prevalence and severity of ill-health. The …

Background Reliable and timely information on the leading causes of death in populations,
and how these are changing, is a crucial input into health policy debates. In the Global …

Objective To estimate the global burden of hip and knee osteoarthritis (OA) as part of the
Global Burden of Disease 2010 study and to explore how the burden of hip and knee OA …

Background Measurement of the global burden of disease with disability-adjusted life-years
(DALYs) requires disability weights that quantify health losses for all non-fatal …

Peroxisomes have long been established to play a central role in regulating various metabolic
activities in mammalian cells. These organelles act in concert with mitochondria to control …

Background Current international treatment guidelines recommending therapeutic exercise
for people with symptomatic hip osteoarthritis (OA) report are based on limited evidence. …