Hippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest

…, H Aghajanian, KA Engleka, LY Lim… - …, 2015 - journals.biologists.com
Notch signaling has well-defined roles in the assembly of arterial walls and in the development
of the endothelium and smooth muscle of the vasculature. Hippo signaling regulates …

[HTML][HTML] Genetic blockade of lymphangiogenesis does not impair cardiac function after myocardial infarction

TCS Keller, L Lim, SV Shewale… - The Journal of …, 2021 - Am Soc Clin Investig
In recent decades, treatments for myocardial infarction (MI), such as stem and progenitor
cell therapy, have attracted considerable scientific and clinical attention but failed to improve …

[PDF][PDF] From childhood to adulthood: the trajectory of damage in patients with juvenile‐onset systemic lupus erythematosus

LSH Lim, E Pullenayegum, L Lim… - Arthritis care & …, 2017 - Wiley Online Library
Objective To determine the longitudinal damage trajectory of patients with juvenile‐onset
systemic lupus erythematosus ( SLE ), and to identify baseline and disease course predictors …

[HTML][HTML] Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis

…, S Bamezai, M Oxendine, L Lim… - The Journal of …, 2019 - Am Soc Clin Investig
Deep venous thrombosis (DVT) and secondary pulmonary embolism cause approximately
100,000 deaths per year in the United States. Physical immobility is the most significant risk …

[HTML][HTML] Lymphatic mimicry in maternal endothelial cells promotes placental spiral artery remodeling

JB Pawlak, L Bálint, L Lim, W Ma… - The Journal of …, 2019 - Am Soc Clin Investig
Molecular heterogeneity of endothelial cells underlies their highly specialized functions during
changing physiological conditions within diverse vascular beds. For example, placental …

Hemostasis stimulates lymphangiogenesis through release and activation of VEGFC

L Lim, H Bui, O Farrelly, J Yang, L Li… - Blood, The Journal …, 2019 - ashpublications.org
Hemostasis associated with tissue injury is followed by wound healing, a complex process
by which damaged cellular material is removed and tissue repaired. Angiogenic responses …

[HTML][HTML] Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow

…, J Kazenwadel, A Oszmiana, L Lim… - The Journal of …, 2020 - Am Soc Clin Investig
The atypical cadherin FAT4 has established roles in the regulation of planar cell polarity and
Hippo pathway signaling that are cell context dependent. The recent identification of FAT4 …

Phosphoregulatory protein 14-3-3 facilitates SAC1 transport from the endoplasmic reticulum

…, A Blagoveshchenskaya, L Lim… - Proceedings of the …, 2015 - National Acad Sciences
Most secretory cargo proteins in eukaryotes are synthesized in the endoplasmic reticulum
and actively exported in membrane-bound vesicles that are formed by the cytosolic coat …

Prevalence of Shiga toxin-producing Escherichia coli as detected by enzyme-linked immunoassays and real-time PCR during the summer months in northern Alberta …

L Chui, MC Lee, K Malejczyk, L Lim… - Journal of Clinical …, 2011 - Am Soc Microbiol
Shiga toxin-producing Escherichia coli (STEC) in northern Alberta was detected using two
enzyme immunoassays and an in-house real-time PCR. Of 2,328 stool samples, 8 were …

Manufacturing clinical‐grade human induced pluripotent stem cell‐derived beta cells for diabetes treatment

LS Tan, JT Chen, LY Lim, AKK Teo - Cell Proliferation, 2022 - Wiley Online Library
The unlimited proliferative capacity of human pluripotent stem cells (hPSCs) fortifies it as
one of the most attractive sources for cell therapy application in diabetes. In the past two …